A General Catalytic Route to Enantioenriched Isoindolinones and Phthalides: Application in the Synthesis of (S)-PD 172938
Publication type: Journal Article
Publication date: 2019-01-09
scimago Q1
wos Q1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
30624068
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
Chiral Brønsted acid catalyzed enantioselective syntheses of isoindolinones and phthalides have been accomplished via tandem Mannich-lactamization and aldol-lactonization reactions, respectively. A variety of enantioenriched isoindolinones (up to 99% ee) and phthalides (up to 85% ee) containing α-diazoesters were afforded in excellent yields. Furthermore, a concise synthesis of ( S)-PD 172938 has been demonstrated by using this protocol.
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Total citations:
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Citations from 2024:
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(11.11%)
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GOST
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Ray S. K. et al. A General Catalytic Route to Enantioenriched Isoindolinones and Phthalides: Application in the Synthesis of (S)-PD 172938 // Organic Letters. 2019. Vol. 21. No. 2. pp. 417-422.
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Ray S. K., Sadhu M. M., Biswas R. G., Unhale R. A., Z.P. R. A General Catalytic Route to Enantioenriched Isoindolinones and Phthalides: Application in the Synthesis of (S)-PD 172938 // Organic Letters. 2019. Vol. 21. No. 2. pp. 417-422.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/acs.orglett.8b03597
UR - https://doi.org/10.1021/acs.orglett.8b03597
TI - A General Catalytic Route to Enantioenriched Isoindolinones and Phthalides: Application in the Synthesis of (S)-PD 172938
T2 - Organic Letters
AU - Ray, Sumit K
AU - Sadhu, Milon M
AU - Biswas, Rayhan G
AU - Unhale, Rajshekhar A
AU - Z.P., Rybnikova
PY - 2019
DA - 2019/01/09
PB - American Chemical Society (ACS)
SP - 417-422
IS - 2
VL - 21
PMID - 30624068
SN - 1523-7060
SN - 1523-7052
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2019_Ray,
author = {Sumit K Ray and Milon M Sadhu and Rayhan G Biswas and Rajshekhar A Unhale and Rybnikova Z.P.},
title = {A General Catalytic Route to Enantioenriched Isoindolinones and Phthalides: Application in the Synthesis of (S)-PD 172938},
journal = {Organic Letters},
year = {2019},
volume = {21},
publisher = {American Chemical Society (ACS)},
month = {jan},
url = {https://doi.org/10.1021/acs.orglett.8b03597},
number = {2},
pages = {417--422},
doi = {10.1021/acs.orglett.8b03597}
}
Cite this
MLA
Copy
Ray, Sumit K., et al. “A General Catalytic Route to Enantioenriched Isoindolinones and Phthalides: Application in the Synthesis of (S)-PD 172938.” Organic Letters, vol. 21, no. 2, Jan. 2019, pp. 417-422. https://doi.org/10.1021/acs.orglett.8b03597.
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