Accounts of Chemical Research, volume 44, issue 9, pages 651-653

A Decade of Bioorthogonal Chemistry

Publication typeJournal Article
Publication date2011-09-20
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor18.3
ISSN00014842, 15204898
General Chemistry
General Medicine
Abstract
Inventing new chemical reactions is a long-standing passion of chemists, as reflected in the ever-popular field of reaction methodology. Historically, the environment in which newly crafted transformations would be performed imposed minimal limitations on reaction design; after all, solvents can be screened to find an optimal choice, temperature can be modulated, air and moisture can be excluded, catalysts can be added, competing functional groups can be protected, and byproducts can be siphoned away. Such flexibility permitted the use of diverse reagents and conditions, culminating in a vast compendium of synthetic transformations that has been wielded to produce myriad complex chemical structures. The target-driven synthetic chemist now enjoys an impressive reaction toolkit. But what if the challenge were inverted, wherein the target structure was relatively simple but the environment in which the necessary reactions must proceed was so chemically complex and uncontrollable that no two functional groups could combine reliably and selectively under such conditions?

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GOST |
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GOST Copy
Bertozzi C. R. A Decade of Bioorthogonal Chemistry // Accounts of Chemical Research. 2011. Vol. 44. No. 9. pp. 651-653.
GOST all authors (up to 50) Copy
Bertozzi C. R. A Decade of Bioorthogonal Chemistry // Accounts of Chemical Research. 2011. Vol. 44. No. 9. pp. 651-653.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1021/ar200193f
UR - https://doi.org/10.1021/ar200193f
TI - A Decade of Bioorthogonal Chemistry
T2 - Accounts of Chemical Research
AU - Bertozzi, Carolyn R.
PY - 2011
DA - 2011/09/20 00:00:00
PB - American Chemical Society (ACS)
SP - 651-653
IS - 9
VL - 44
SN - 0001-4842
SN - 1520-4898
ER -
BibTex |
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BibTex Copy
@article{2011_Bertozzi,
author = {Carolyn R. Bertozzi},
title = {A Decade of Bioorthogonal Chemistry},
journal = {Accounts of Chemical Research},
year = {2011},
volume = {44},
publisher = {American Chemical Society (ACS)},
month = {sep},
url = {https://doi.org/10.1021/ar200193f},
number = {9},
pages = {651--653},
doi = {10.1021/ar200193f}
}
MLA
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MLA Copy
Bertozzi, Carolyn R.. “A Decade of Bioorthogonal Chemistry.” Accounts of Chemical Research, vol. 44, no. 9, Sep. 2011, pp. 651-653. https://doi.org/10.1021/ar200193f.
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