Novel Near-Infrared Cyanine Fluorochromes: Synthesis, Properties, and Bioconjugation
Тип публикации: Journal Article
Дата публикации: 2002-04-17
scimago Q1
wos Q1
БС1
SJR: 1.035
CiteScore: 7.5
Impact factor: 3.9
ISSN: 10431802, 15204812
PubMed ID:
12009952
Organic Chemistry
Pharmacology
Pharmaceutical Science
Biotechnology
Bioengineering
Biomedical Engineering
Краткое описание
Recently, near-infrared (NIR) fluorescence light has been applied to image various biological events in vivo, because it penetrates tissue more efficiently than light in the visible spectrum. Compounds exhibiting fluorescent properties in the NIR range are key elements for this upcoming optical imaging technology. In this paper, we report the synthesis of four new, water-soluble NIR cyanine fluorochromes which have superior chemical stability and optical properties. Each fluorochrome was designed with a monoreactive carboxyl group for labeling purposes. When multiple fluorochromes were attached to a single macromolecule, fluorescence quenching was observed. On the basis of this property, a novel autoquenched enzyme sensitive NIR fluorescence probe was prepared.
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Метрики
139
Всего цитирований:
139
Цитирований c 2025:
4
(2.88%)
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MLA
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ГОСТ
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LIN Y., Weissleder R., Tung C. Novel Near-Infrared Cyanine Fluorochromes: Synthesis, Properties, and Bioconjugation // Bioconjugate Chemistry. 2002. Vol. 13. No. 3. pp. 605-610.
ГОСТ со всеми авторами (до 50)
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LIN Y., Weissleder R., Tung C. Novel Near-Infrared Cyanine Fluorochromes: Synthesis, Properties, and Bioconjugation // Bioconjugate Chemistry. 2002. Vol. 13. No. 3. pp. 605-610.
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RIS
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TY - JOUR
DO - 10.1021/bc0155723
UR - https://doi.org/10.1021/bc0155723
TI - Novel Near-Infrared Cyanine Fluorochromes: Synthesis, Properties, and Bioconjugation
T2 - Bioconjugate Chemistry
AU - LIN, YUHUI
AU - Weissleder, Ralph
AU - Tung, Ching-Ju
PY - 2002
DA - 2002/04/17
PB - American Chemical Society (ACS)
SP - 605-610
IS - 3
VL - 13
PMID - 12009952
SN - 1043-1802
SN - 1520-4812
ER -
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BibTex (до 50 авторов)
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@article{2002_LIN,
author = {YUHUI LIN and Ralph Weissleder and Ching-Ju Tung},
title = {Novel Near-Infrared Cyanine Fluorochromes: Synthesis, Properties, and Bioconjugation},
journal = {Bioconjugate Chemistry},
year = {2002},
volume = {13},
publisher = {American Chemical Society (ACS)},
month = {apr},
url = {https://doi.org/10.1021/bc0155723},
number = {3},
pages = {605--610},
doi = {10.1021/bc0155723}
}
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MLA
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LIN, YUHUI, et al. “Novel Near-Infrared Cyanine Fluorochromes: Synthesis, Properties, and Bioconjugation.” Bioconjugate Chemistry, vol. 13, no. 3, Apr. 2002, pp. 605-610. https://doi.org/10.1021/bc0155723.