volume 103 issue 11 pages 3215-3217

Asymmetric total synthesis of erythromycin. 3. Total synthesis of erythromycin

R B Woodward
E Logusch
K. P. Nambiar
K Sakan
D. E. Ward
B W Au Yeung
P Balaram
L J Browne
P. J. Card
C H Chen
Publication typeJournal Article
Publication date1981-06-01
scimago Q1
wos Q1
SJR5.554
CiteScore22.5
Impact factor15.6
ISSN00027863, 15205126
General Chemistry
Catalysis
Biochemistry
Colloid and Surface Chemistry
Abstract
In the preceding paper' we described the preparation of the key lactone intermediate la in optically active form. In this paper we report the synthesis of erythromycin (2) from la. In essence,this transformation involves the glycosidation of a suitable derivative of la with L-cladinose and D-desosamine and the generation of the C-9 ketone functionality.
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GOST |
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GOST Copy
Woodward R. B. et al. Asymmetric total synthesis of erythromycin. 3. Total synthesis of erythromycin // Journal of the American Chemical Society. 1981. Vol. 103. No. 11. pp. 3215-3217.
GOST all authors (up to 50) Copy
Woodward R. B., Logusch E., Nambiar K. P., Sakan K., Ward D. E., Au Yeung B. W., Balaram P., Browne L. J., Card P. J., Chen C. H. Asymmetric total synthesis of erythromycin. 3. Total synthesis of erythromycin // Journal of the American Chemical Society. 1981. Vol. 103. No. 11. pp. 3215-3217.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/ja00401a051
UR - https://doi.org/10.1021/ja00401a051
TI - Asymmetric total synthesis of erythromycin. 3. Total synthesis of erythromycin
T2 - Journal of the American Chemical Society
AU - Woodward, R B
AU - Logusch, E
AU - Nambiar, K. P.
AU - Sakan, K
AU - Ward, D. E.
AU - Au Yeung, B W
AU - Balaram, P
AU - Browne, L J
AU - Card, P. J.
AU - Chen, C H
PY - 1981
DA - 1981/06/01
PB - American Chemical Society (ACS)
SP - 3215-3217
IS - 11
VL - 103
SN - 0002-7863
SN - 1520-5126
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{1981_Woodward,
author = {R B Woodward and E Logusch and K. P. Nambiar and K Sakan and D. E. Ward and B W Au Yeung and P Balaram and L J Browne and P. J. Card and C H Chen},
title = {Asymmetric total synthesis of erythromycin. 3. Total synthesis of erythromycin},
journal = {Journal of the American Chemical Society},
year = {1981},
volume = {103},
publisher = {American Chemical Society (ACS)},
month = {jun},
url = {https://doi.org/10.1021/ja00401a051},
number = {11},
pages = {3215--3217},
doi = {10.1021/ja00401a051}
}
MLA
Cite this
MLA Copy
Woodward, R. B., et al. “Asymmetric total synthesis of erythromycin. 3. Total synthesis of erythromycin.” Journal of the American Chemical Society, vol. 103, no. 11, Jun. 1981, pp. 3215-3217. https://doi.org/10.1021/ja00401a051.