Φ-Values beyond the Ribosomally Encoded Amino Acids: Kinetic and Thermodynamic Consequences of Incorporating Trifluoromethyl Amino Acids in a Globular Protein
Тип публикации: Journal Article
Дата публикации: 2003-07-11
scimago Q1
wos Q1
БС1
SJR: 5.489
CiteScore: 24.4
Impact factor: 15.6
ISSN: 00027863, 15205126
PubMed ID:
12889945
General Chemistry
Catalysis
Biochemistry
Colloid and Surface Chemistry
Краткое описание
The consequences of the substitution of 4,4,4-trifluorovaline for valine on the folding kinetics and thermodynamics of a globular protein are presented. Variants of the N-terminal domain of L9, a small alpha-beta protein, were prepared in which V3 or V21 was replaced by trifluorovaline. CD and NMR demonstrate that the structure is not perturbed. Both are more stable, the V3 variant by 0.8 kcal mol-1 and the V21 variant by 1.4 kcal mol-1. The increase of stability is significantly larger than that observed in coiled-coils on a per trifluoromethyl group basis. Folding is two-state, and the variants both fold faster than the wild type. The Phi-values are 0.16 and 0.11, respectively.
Найдено
Ничего не найдено, попробуйте изменить настройки фильтра.
Для доступа к списку цитирований публикации необходимо авторизоваться.
Для доступа к списку профилей, цитирующих публикацию, необходимо авторизоваться.
Топ-30
Журналы
|
1
2
3
4
5
|
|
|
Journal of the American Chemical Society
5 публикаций, 7.94%
|
|
|
Organic and Biomolecular Chemistry
4 публикации, 6.35%
|
|
|
Journal of Fluorine Chemistry
3 публикации, 4.76%
|
|
|
Russian Chemical Bulletin
3 публикации, 4.76%
|
|
|
Biochemistry
3 публикации, 4.76%
|
|
|
Journal of Molecular Biology
2 публикации, 3.17%
|
|
|
Chemistry - A European Journal
2 публикации, 3.17%
|
|
|
Journal of Organic Chemistry
2 публикации, 3.17%
|
|
|
Journal of Physical Chemistry B
2 публикации, 3.17%
|
|
|
Mendeleev Communications
1 публикация, 1.59%
|
|
|
Pharmaceuticals
1 публикация, 1.59%
|
|
|
Amino Acids
1 публикация, 1.59%
|
|
|
Scientific Reports
1 публикация, 1.59%
|
|
|
PLoS ONE
1 публикация, 1.59%
|
|
|
Progress in Nuclear Magnetic Resonance Spectroscopy
1 публикация, 1.59%
|
|
|
Enzyme and Microbial Technology
1 публикация, 1.59%
|
|
|
Bioorganic and Medicinal Chemistry Letters
1 публикация, 1.59%
|
|
|
Biophysical Journal
1 публикация, 1.59%
|
|
|
ChemBioChem
1 публикация, 1.59%
|
|
|
European Journal of Organic Chemistry
1 публикация, 1.59%
|
|
|
Angewandte Chemie - International Edition
1 публикация, 1.59%
|
|
|
Angewandte Chemie
1 публикация, 1.59%
|
|
|
Helvetica Chimica Acta
1 публикация, 1.59%
|
|
|
Biopolymers
1 публикация, 1.59%
|
|
|
Protein Science
1 публикация, 1.59%
|
|
|
Journal of Peptide Science
1 публикация, 1.59%
|
|
|
Journal of Combinatorial Chemistry
1 публикация, 1.59%
|
|
|
Inorganic Chemistry
1 публикация, 1.59%
|
|
|
Nano Letters
1 публикация, 1.59%
|
|
|
1
2
3
4
5
|
Издатели
|
2
4
6
8
10
12
14
16
|
|
|
American Chemical Society (ACS)
15 публикаций, 23.81%
|
|
|
Elsevier
13 публикаций, 20.63%
|
|
|
Wiley
12 публикаций, 19.05%
|
|
|
Springer Nature
8 публикаций, 12.7%
|
|
|
Royal Society of Chemistry (RSC)
8 публикаций, 12.7%
|
|
|
Taylor & Francis
2 публикации, 3.17%
|
|
|
MDPI
1 публикация, 1.59%
|
|
|
Public Library of Science (PLoS)
1 публикация, 1.59%
|
|
|
Proceedings of the National Academy of Sciences (PNAS)
1 публикация, 1.59%
|
|
|
Cold Spring Harbor Laboratory
1 публикация, 1.59%
|
|
|
Georg Thieme Verlag KG
1 публикация, 1.59%
|
|
|
2
4
6
8
10
12
14
16
|
- Мы не учитываем публикации, у которых нет DOI.
- Статистика публикаций обновляется еженедельно.
Вы ученый?
Создайте профиль, чтобы получать персональные рекомендации коллег, конференций и новых статей.
Метрики
63
Всего цитирований:
63
Цитирований c 2025:
0
Цитировать
ГОСТ |
RIS |
BibTex |
MLA
Цитировать
ГОСТ
Скопировать
Horng J. C., Raleigh D. P. Φ-Values beyond the Ribosomally Encoded Amino Acids: Kinetic and Thermodynamic Consequences of Incorporating Trifluoromethyl Amino Acids in a Globular Protein // Journal of the American Chemical Society. 2003. Vol. 125. No. 31. pp. 9286-9287.
ГОСТ со всеми авторами (до 50)
Скопировать
Horng J. C., Raleigh D. P. Φ-Values beyond the Ribosomally Encoded Amino Acids: Kinetic and Thermodynamic Consequences of Incorporating Trifluoromethyl Amino Acids in a Globular Protein // Journal of the American Chemical Society. 2003. Vol. 125. No. 31. pp. 9286-9287.
Цитировать
RIS
Скопировать
TY - JOUR
DO - 10.1021/ja0353199
UR - https://doi.org/10.1021/ja0353199
TI - Φ-Values beyond the Ribosomally Encoded Amino Acids: Kinetic and Thermodynamic Consequences of Incorporating Trifluoromethyl Amino Acids in a Globular Protein
T2 - Journal of the American Chemical Society
AU - Horng, J. C.
AU - Raleigh, Daniel P.
PY - 2003
DA - 2003/07/11
PB - American Chemical Society (ACS)
SP - 9286-9287
IS - 31
VL - 125
PMID - 12889945
SN - 0002-7863
SN - 1520-5126
ER -
Цитировать
BibTex (до 50 авторов)
Скопировать
@article{2003_Horng,
author = {J. C. Horng and Daniel P. Raleigh},
title = {Φ-Values beyond the Ribosomally Encoded Amino Acids: Kinetic and Thermodynamic Consequences of Incorporating Trifluoromethyl Amino Acids in a Globular Protein},
journal = {Journal of the American Chemical Society},
year = {2003},
volume = {125},
publisher = {American Chemical Society (ACS)},
month = {jul},
url = {https://doi.org/10.1021/ja0353199},
number = {31},
pages = {9286--9287},
doi = {10.1021/ja0353199}
}
Цитировать
MLA
Скопировать
Horng, J. C., and Daniel P. Raleigh. “Φ-Values beyond the Ribosomally Encoded Amino Acids: Kinetic and Thermodynamic Consequences of Incorporating Trifluoromethyl Amino Acids in a Globular Protein.” Journal of the American Chemical Society, vol. 125, no. 31, Jul. 2003, pp. 9286-9287. https://doi.org/10.1021/ja0353199.