BODIPY-based ratiometric fluorescent sensor for highly selective detection of glutathione over cysteine and homocysteine.
Тип публикации: Journal Article
Дата публикации: 2012-11-08
SCImago Q1
Tоп 10% SCImago
WOS Q1
БС1
SJR: 5.491
CiteScore: 22
Impact factor: 16.6
ISSN: 00027863, 15205126
PubMed ID:
23121092
General Chemistry
Catalysis
Biochemistry
Colloid and Surface Chemistry
Краткое описание
We report a ratiometric fluorescent sensor based on monochlorinated BODIPY for highly selective detection of glutathione (GSH) over cysteine (Cys)/homocysteine (Hcy). The chlorine of the monochlorinated BODIPY can be rapidly replaced by thiolates of biothiols through thiol-halogen nucleophilic substitution. The amino groups of Cys/Hcy but not GSH further replace the thiolate to form amino-substituted BODIPY. The significantly different photophysical properties of sulfur- and amino-substituted BODIPY enable the discrimination of GSH over Cys and Hcy. The sensor was applied for detection of GSH in living cells.
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871
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ГОСТ
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Niu L. et al. BODIPY-based ratiometric fluorescent sensor for highly selective detection of glutathione over cysteine and homocysteine. // Journal of the American Chemical Society. 2012. Vol. 134. No. 46. pp. 18928-18931.
ГОСТ со всеми авторами (до 50)
Скопировать
Niu L., Guan Y. S., Chen Y., Wu L., Tung C., Yang Q. BODIPY-based ratiometric fluorescent sensor for highly selective detection of glutathione over cysteine and homocysteine. // Journal of the American Chemical Society. 2012. Vol. 134. No. 46. pp. 18928-18931.
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RIS
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TY - JOUR
DO - 10.1021/ja309079f
UR - https://doi.org/10.1021/ja309079f
TI - BODIPY-based ratiometric fluorescent sensor for highly selective detection of glutathione over cysteine and homocysteine.
T2 - Journal of the American Chemical Society
AU - Niu, Li-Ya
AU - Guan, Ying Shi
AU - Chen, Yuzhe
AU - Wu, Li-Zhu
AU - Tung, Chen-Ho
AU - Yang, Qingzheng
PY - 2012
DA - 2012/11/08
PB - American Chemical Society (ACS)
SP - 18928-18931
IS - 46
VL - 134
PMID - 23121092
SN - 0002-7863
SN - 1520-5126
ER -
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BibTex (до 50 авторов)
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@article{2012_Niu,
author = {Li-Ya Niu and Ying Shi Guan and Yuzhe Chen and Li-Zhu Wu and Chen-Ho Tung and Qingzheng Yang},
title = {BODIPY-based ratiometric fluorescent sensor for highly selective detection of glutathione over cysteine and homocysteine.},
journal = {Journal of the American Chemical Society},
year = {2012},
volume = {134},
publisher = {American Chemical Society (ACS)},
month = {nov},
url = {https://doi.org/10.1021/ja309079f},
number = {46},
pages = {18928--18931},
doi = {10.1021/ja309079f}
}
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MLA
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Niu, Li-Ya, et al. “BODIPY-based ratiometric fluorescent sensor for highly selective detection of glutathione over cysteine and homocysteine..” Journal of the American Chemical Society, vol. 134, no. 46, Nov. 2012, pp. 18928-18931. https://doi.org/10.1021/ja309079f.
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