Cellular Uptake of Gold Nanoparticles Triggered by Host–Guest Interactions
Jesús Mosquera
1
,
Malou Henriksen-Lacey
1
,
Isabel Amores García
1
,
Jéssica Rodríguez
2
,
Luis Liz-Marzan
1, 3
1
Publication type: Journal Article
Publication date: 2018-03-21
scimago Q1
wos Q1
SJR: 5.554
CiteScore: 22.5
Impact factor: 15.6
ISSN: 00027863, 15205126
PubMed ID:
29562135
General Chemistry
Catalysis
Biochemistry
Colloid and Surface Chemistry
Abstract
We describe an approach to regulate the cellular uptake of small gold nanoparticles using supramolecular chemistry. The strategy relies on the functionalization of AuNPs with negatively charged pyranines, which largely hamper their penetration in cells. Cellular uptake can be activated in situ through the addition of cationic covalent cages that specifically recognize the fluorescent pyranine dyes and counterbalance the negative charges. The high selectivity and reversibility of the host-guest recognition activates cellular uptake, even in protein-rich biological media, as well as its regulation by rational addition of either cage or pyranine.
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Metrics
65
Total citations:
65
Citations from 2024:
6
(9%)
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MLA
Cite this
GOST
Copy
Mosquera J. et al. Cellular Uptake of Gold Nanoparticles Triggered by Host–Guest Interactions // Journal of the American Chemical Society. 2018. Vol. 140. No. 13. pp. 4469-4472.
GOST all authors (up to 50)
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Mosquera J., Henriksen-Lacey M., Amores García I., Martínez Calvo M., Rodríguez J., Mascareñas J. L., Liz-Marzan L. Cellular Uptake of Gold Nanoparticles Triggered by Host–Guest Interactions // Journal of the American Chemical Society. 2018. Vol. 140. No. 13. pp. 4469-4472.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/jacs.7b12505
UR - https://doi.org/10.1021/jacs.7b12505
TI - Cellular Uptake of Gold Nanoparticles Triggered by Host–Guest Interactions
T2 - Journal of the American Chemical Society
AU - Mosquera, Jesús
AU - Henriksen-Lacey, Malou
AU - Amores García, Isabel
AU - Martínez Calvo, Miguel
AU - Rodríguez, Jéssica
AU - Mascareñas, José L.
AU - Liz-Marzan, Luis
PY - 2018
DA - 2018/03/21
PB - American Chemical Society (ACS)
SP - 4469-4472
IS - 13
VL - 140
PMID - 29562135
SN - 0002-7863
SN - 1520-5126
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2018_Mosquera,
author = {Jesús Mosquera and Malou Henriksen-Lacey and Isabel Amores García and Miguel Martínez Calvo and Jéssica Rodríguez and José L. Mascareñas and Luis Liz-Marzan},
title = {Cellular Uptake of Gold Nanoparticles Triggered by Host–Guest Interactions},
journal = {Journal of the American Chemical Society},
year = {2018},
volume = {140},
publisher = {American Chemical Society (ACS)},
month = {mar},
url = {https://doi.org/10.1021/jacs.7b12505},
number = {13},
pages = {4469--4472},
doi = {10.1021/jacs.7b12505}
}
Cite this
MLA
Copy
Mosquera, Jesús, et al. “Cellular Uptake of Gold Nanoparticles Triggered by Host–Guest Interactions.” Journal of the American Chemical Society, vol. 140, no. 13, Mar. 2018, pp. 4469-4472. https://doi.org/10.1021/jacs.7b12505.