Antiparasitic agents. 3. Synthesis and anthelmintic activities of novel 2-pyridinyl-5-isothiocyanatobenzimidazoles
Тип публикации: Journal Article
Дата публикации: 1979-09-01
scimago Q1
wos Q1
БС1
SJR: 1.801
CiteScore: 11.5
Impact factor: 6.8
ISSN: 00222623, 15204804
PubMed ID:
490558
Drug Discovery
Molecular Medicine
Краткое описание
The preparation and anthelmintic activities of a series of 2-pyridinyl-5-isothiocyanatobenzimidazoles are described. In the primary oral mouse screen, six derivatives showed 100% taeniacidal activity at 0.2% in diet. The most active member in this series, 1c, is potentially an effective gastrointestinal nematocide in sheep at 50 mg/kg po.
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ГОСТ
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Haugwitz R. D. et al. Antiparasitic agents. 3. Synthesis and anthelmintic activities of novel 2-pyridinyl-5-isothiocyanatobenzimidazoles // Journal of Medicinal Chemistry. 1979. Vol. 22. No. 9. pp. 1113-1118.
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Haugwitz R. D., Maurer B. V., JACOBS G. A., Narayanan V. L., Cruthers L., Szanto J. Antiparasitic agents. 3. Synthesis and anthelmintic activities of novel 2-pyridinyl-5-isothiocyanatobenzimidazoles // Journal of Medicinal Chemistry. 1979. Vol. 22. No. 9. pp. 1113-1118.
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TY - JOUR
DO - 10.1021/jm00195a021
UR - https://doi.org/10.1021/jm00195a021
TI - Antiparasitic agents. 3. Synthesis and anthelmintic activities of novel 2-pyridinyl-5-isothiocyanatobenzimidazoles
T2 - Journal of Medicinal Chemistry
AU - Haugwitz, R. D.
AU - Maurer, B V
AU - JACOBS, G A
AU - Narayanan, V L
AU - Cruthers, L
AU - Szanto, J.
PY - 1979
DA - 1979/09/01
PB - American Chemical Society (ACS)
SP - 1113-1118
IS - 9
VL - 22
PMID - 490558
SN - 0022-2623
SN - 1520-4804
ER -
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@article{1979_Haugwitz,
author = {R. D. Haugwitz and B V Maurer and G A JACOBS and V L Narayanan and L Cruthers and J. Szanto},
title = {Antiparasitic agents. 3. Synthesis and anthelmintic activities of novel 2-pyridinyl-5-isothiocyanatobenzimidazoles},
journal = {Journal of Medicinal Chemistry},
year = {1979},
volume = {22},
publisher = {American Chemical Society (ACS)},
month = {sep},
url = {https://doi.org/10.1021/jm00195a021},
number = {9},
pages = {1113--1118},
doi = {10.1021/jm00195a021}
}
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MLA
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Haugwitz, R. D., et al. “Antiparasitic agents. 3. Synthesis and anthelmintic activities of novel 2-pyridinyl-5-isothiocyanatobenzimidazoles.” Journal of Medicinal Chemistry, vol. 22, no. 9, Sep. 1979, pp. 1113-1118. https://doi.org/10.1021/jm00195a021.