Preparation of 8-Amido-2-dimethylamino-1,2,3,4-tetrahydro-2-dibenzofurans and Several Fluorinated Derivatives via [3,3]-Sigmatropic Rearrangement of O-Aryloximes
Тип публикации: Journal Article
Дата публикации: 2003-01-04
scimago Q2
wos Q1
БС1
SJR: 0.737
CiteScore: 6.1
Impact factor: 3.6
ISSN: 00223263, 15206904
PubMed ID:
12558398
Organic Chemistry
Краткое описание
Methodology to prepare 8-amido-2-amino-1,2,3,4-tetrahydro-2-dibenzofurans, analogues with a fluorine substituent incorporated in the 6-, 7-, and 9-positions, and a difluorinated analogue with fluorines in the 6- and 9-positions is described. The tetrahydrodibenzofuran ring systems are prepared by acid-catalyzed [3,3]-sigmatropic rearrangement of O-aryloximes. Regioselective reactions to prepare the requisite O-aryloxime intermediates from commercially available fluorobenzene derivatives are discussed.
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Guzzo P. R. et al. Preparation of 8-Amido-2-dimethylamino-1,2,3,4-tetrahydro-2-dibenzofurans and Several Fluorinated Derivatives via [3,3]-Sigmatropic Rearrangement of O-Aryloximes // Journal of Organic Chemistry. 2003. Vol. 68. No. 3. pp. 770-778.
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Guzzo P. R., Buckle R. N., Chou M., Dinn S. R., Flaugh M. E., Kiefer A. D., Ryter K. T., Sampognaro A. J., Tregay S. W., Xu Y. Preparation of 8-Amido-2-dimethylamino-1,2,3,4-tetrahydro-2-dibenzofurans and Several Fluorinated Derivatives via [3,3]-Sigmatropic Rearrangement of O-Aryloximes // Journal of Organic Chemistry. 2003. Vol. 68. No. 3. pp. 770-778.
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TY - JOUR
DO - 10.1021/jo020600b
UR - https://doi.org/10.1021/jo020600b
TI - Preparation of 8-Amido-2-dimethylamino-1,2,3,4-tetrahydro-2-dibenzofurans and Several Fluorinated Derivatives via [3,3]-Sigmatropic Rearrangement of O-Aryloximes
T2 - Journal of Organic Chemistry
AU - Guzzo, Peter R
AU - Buckle, Ronald N
AU - Chou, Ming
AU - Dinn, Sean R.
AU - Flaugh, Michael E.
AU - Kiefer, Anton D
AU - Ryter, Kendal T.
AU - Sampognaro, Anthony J
AU - Tregay, Steven W
AU - Xu, Yao-Chang
PY - 2003
DA - 2003/01/04
PB - American Chemical Society (ACS)
SP - 770-778
IS - 3
VL - 68
PMID - 12558398
SN - 0022-3263
SN - 1520-6904
ER -
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@article{2003_Guzzo,
author = {Peter R Guzzo and Ronald N Buckle and Ming Chou and Sean R. Dinn and Michael E. Flaugh and Anton D Kiefer and Kendal T. Ryter and Anthony J Sampognaro and Steven W Tregay and Yao-Chang Xu},
title = {Preparation of 8-Amido-2-dimethylamino-1,2,3,4-tetrahydro-2-dibenzofurans and Several Fluorinated Derivatives via [3,3]-Sigmatropic Rearrangement of O-Aryloximes},
journal = {Journal of Organic Chemistry},
year = {2003},
volume = {68},
publisher = {American Chemical Society (ACS)},
month = {jan},
url = {https://doi.org/10.1021/jo020600b},
number = {3},
pages = {770--778},
doi = {10.1021/jo020600b}
}
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Guzzo, Peter R., et al. “Preparation of 8-Amido-2-dimethylamino-1,2,3,4-tetrahydro-2-dibenzofurans and Several Fluorinated Derivatives via [3,3]-Sigmatropic Rearrangement of O-Aryloximes.” Journal of Organic Chemistry, vol. 68, no. 3, Jan. 2003, pp. 770-778. https://doi.org/10.1021/jo020600b.