том 75 издание 12 страницы 4288-4291

Facile iterative synthesis of 2,5-terpyrimidinylenes as nonpeptidic alpha-helical mimics.

Тип публикацииJournal Article
Дата публикации2010-05-14
scimago Q2
wos Q1
БС1
SJR0.737
CiteScore6.1
Impact factor3.6
ISSN00223263, 15206904
Organic Chemistry
Краткое описание
A facile iterative synthesis of 2,5-terpyrimidinylenes that are structurally analogous to alpha-helix mimics is presented. Condensation of amidines with readily prepared alpha,beta-unsaturated alpha-cyanoketones gives 5-cyano-substituted pyrimidines. Iterative transformation of the 5-cyano group into an amidine allows synthesis of 2,5-terpyrimidinylenes with variable groups at the 4-, 4'-, and 4''-positions. These compounds are designed to mimic the i, i + 4, and i + 7 sites of an alpha-helix.
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ГОСТ |
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Anderson L. et al. Facile iterative synthesis of 2,5-terpyrimidinylenes as nonpeptidic alpha-helical mimics. // Journal of Organic Chemistry. 2010. Vol. 75. No. 12. pp. 4288-4291.
ГОСТ со всеми авторами (до 50) Скопировать
Anderson L., Zhou M., Sharma V., McLaughlin J. M., Santiago D. N., Fronczek F., Guida W. C., Mclaughlin M. Facile iterative synthesis of 2,5-terpyrimidinylenes as nonpeptidic alpha-helical mimics. // Journal of Organic Chemistry. 2010. Vol. 75. No. 12. pp. 4288-4291.
RIS |
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TY - JOUR
DO - 10.1021/jo100272d
UR - https://doi.org/10.1021/jo100272d
TI - Facile iterative synthesis of 2,5-terpyrimidinylenes as nonpeptidic alpha-helical mimics.
T2 - Journal of Organic Chemistry
AU - Anderson, Laura
AU - Zhou, Mingzhou
AU - Sharma, Vasudha
AU - McLaughlin, Jillian M.
AU - Santiago, Daniel N
AU - Fronczek, Frank
AU - Guida, W. C.
AU - Mclaughlin, Mark
PY - 2010
DA - 2010/05/14
PB - American Chemical Society (ACS)
SP - 4288-4291
IS - 12
VL - 75
PMID - 20469918
SN - 0022-3263
SN - 1520-6904
ER -
BibTex |
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BibTex (до 50 авторов) Скопировать
@article{2010_Anderson,
author = {Laura Anderson and Mingzhou Zhou and Vasudha Sharma and Jillian M. McLaughlin and Daniel N Santiago and Frank Fronczek and W. C. Guida and Mark Mclaughlin},
title = {Facile iterative synthesis of 2,5-terpyrimidinylenes as nonpeptidic alpha-helical mimics.},
journal = {Journal of Organic Chemistry},
year = {2010},
volume = {75},
publisher = {American Chemical Society (ACS)},
month = {may},
url = {https://doi.org/10.1021/jo100272d},
number = {12},
pages = {4288--4291},
doi = {10.1021/jo100272d}
}
MLA
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Anderson, Laura, et al. “Facile iterative synthesis of 2,5-terpyrimidinylenes as nonpeptidic alpha-helical mimics..” Journal of Organic Chemistry, vol. 75, no. 12, May. 2010, pp. 4288-4291. https://doi.org/10.1021/jo100272d.