Journal of Organic Chemistry, volume 73, issue 20, pages 8089-8092
Ring-Enlargement of Dimethylaminopropenoyl Cyclopropanes: An Efficient Route to Substituted 2,3-Dihydrofurans
Publication type: Journal Article
Publication date: 2008-09-18
Journal:
Journal of Organic Chemistry
Q2
Q1
SJR: 0.724
CiteScore: 6.2
Impact factor: 3.3
ISSN: 00223263, 15206904
Organic Chemistry
Abstract
A convenient and efficient synthesis of substituted dihydrofurans is developed via ring-enlargement of 1-dimethylaminopropenoyl-1-carbamoyl/benzoyl cyclopropanes catalyzed by ammonium acetate in acetic acid with high regio- and stereoselectivity. Some of the newly synthesized substituted dihydrofurans are subjected to further synthetic transformation in the presence of NaOH (aq) in ethanol to afford the corresponding 5-aryl-2,3-dihydrofuro[3,2-c]pyridin-4(5H)-ones in high yields.
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GOST
Copy
Zhang R. et al. Ring-Enlargement of Dimethylaminopropenoyl Cyclopropanes: An Efficient Route to Substituted 2,3-Dihydrofurans // Journal of Organic Chemistry. 2008. Vol. 73. No. 20. pp. 8089-8092.
GOST all authors (up to 50)
Copy
Zhang R., Liang Y., Zhou G., Wang K., Dong D. Ring-Enlargement of Dimethylaminopropenoyl Cyclopropanes: An Efficient Route to Substituted 2,3-Dihydrofurans // Journal of Organic Chemistry. 2008. Vol. 73. No. 20. pp. 8089-8092.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/jo801289p
UR - https://doi.org/10.1021/jo801289p
TI - Ring-Enlargement of Dimethylaminopropenoyl Cyclopropanes: An Efficient Route to Substituted 2,3-Dihydrofurans
T2 - Journal of Organic Chemistry
AU - Zhang, Rui
AU - Liang, Yongjiu
AU - Zhou, Guang-Yuan
AU - Wang, Kewei
AU - Dong, Dewen
PY - 2008
DA - 2008/09/18
PB - American Chemical Society (ACS)
SP - 8089-8092
IS - 20
VL - 73
SN - 0022-3263
SN - 1520-6904
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2008_Zhang,
author = {Rui Zhang and Yongjiu Liang and Guang-Yuan Zhou and Kewei Wang and Dewen Dong},
title = {Ring-Enlargement of Dimethylaminopropenoyl Cyclopropanes: An Efficient Route to Substituted 2,3-Dihydrofurans},
journal = {Journal of Organic Chemistry},
year = {2008},
volume = {73},
publisher = {American Chemical Society (ACS)},
month = {sep},
url = {https://doi.org/10.1021/jo801289p},
number = {20},
pages = {8089--8092},
doi = {10.1021/jo801289p}
}
Cite this
MLA
Copy
Zhang, Rui, et al. “Ring-Enlargement of Dimethylaminopropenoyl Cyclopropanes: An Efficient Route to Substituted 2,3-Dihydrofurans.” Journal of Organic Chemistry, vol. 73, no. 20, Sep. 2008, pp. 8089-8092. https://doi.org/10.1021/jo801289p.