Langmuir

, volume 22 , issue 1 , pages 2-5

Modification of Gold Nanorods Using Phosphatidylcholine to Reduce Cytotoxicity

Hironobu Takahashi ¹

Yasuro Niidome ¹

Takuro Niidome ¹

Kenji Kaneko ¹

Hideya Kawasaki ¹

Sunao Yamada ¹

Hide authors affiliations Show authors affiliations: 1 affiliation

Department of Materials Physics and Chemistry, Graduate School of Engineering, Kyushu University, Hakozaki, Fukuoka 812-8581, Japan, Department of Applied Chemistry, Faculty of Engineering, Kyushu University, Hakozaki, Fukuoka 812-8581, Japan, Center of Future Chemistry, Kyushu University, Hakozaki, Fukuoka 812-8581, Japan, HVEM Laboratory, Kyushu University, Hakozaki, Fukuoka 812-8581, Japan, and Department of Chemistry, Faculty of Science, Kyushu University, Hakozaki, Fukuoka 812-8581, Japan |

Publication type: Journal Article

Publication date: 2005-11-24

American Chemical Society (ACS)

Langmuir

scimago Q1

wos Q2

SJR: 0.763

CiteScore: 6.0

Impact factor: 3.9

ISSN: 07437463, 15205827

DOI: 10.1021/la0520029

Copy DOI

PubMed ID: 16378388

Spectroscopy

Electrochemistry

Condensed Matter Physics

General Materials Science

Surfaces and Interfaces

Abstract

Hexadecyltrimethylammonium bromide (CTAB), which is necessary for the preparation of gold nanorods (NRs), was extracted from a NR solution into a chloroform phase containing phosphatidylcholine (PC). After three extractions, the zeta potential of the NRs remained positive, but its magnitude decreased from +67 +/- 1 to +15 +/- 1 mV. Transmission electron microscopy and energy-dispersive X-ray analysis indicated that the NRs were passivated with PC. The PC layer on the NR surface contributed to the prevention of NR aggregation. The PC-passivated NRs showed low cytotoxicity in comparison with twice-centrifuged NRs. It was shown that a negligible amount of CTAB was dispersed in the NR solution after the extraction. The extraction using a chloroform phase containing PC was found to be a convenient way of replacing the CTAB with alternative capping agents such as PC. This is a key technique for preparing functional NRs that can have practical applications.

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Pyshnaya Inna

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GOST |

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GOST Copy

Takahashi H. et al. Modification of Gold Nanorods Using Phosphatidylcholine to Reduce Cytotoxicity // Langmuir. 2005. Vol. 22. No. 1. pp. 2-5.

GOST all authors (up to 50) Copy

Takahashi H., Niidome Y., Niidome T., Kaneko K., Kawasaki H., Yamada S. Modification of Gold Nanorods Using Phosphatidylcholine to Reduce Cytotoxicity // Langmuir. 2005. Vol. 22. No. 1. pp. 2-5.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1021/la0520029

UR - https://doi.org/10.1021/la0520029

TI - Modification of Gold Nanorods Using Phosphatidylcholine to Reduce Cytotoxicity

T2 - Langmuir

AU - Takahashi, Hironobu

AU - Niidome, Yasuro

AU - Niidome, Takuro

AU - Kaneko, Kenji

AU - Kawasaki, Hideya

AU - Yamada, Sunao

PY - 2005

DA - 2005/11/24

PB - American Chemical Society (ACS)

SP - 2-5

IS - 1

VL - 22

PMID - 16378388

SN - 0743-7463

SN - 1520-5827

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2005_Takahashi,

author = {Hironobu Takahashi and Yasuro Niidome and Takuro Niidome and Kenji Kaneko and Hideya Kawasaki and Sunao Yamada},

title = {Modification of Gold Nanorods Using Phosphatidylcholine to Reduce Cytotoxicity},

journal = {Langmuir},

year = {2005},

volume = {22},

publisher = {American Chemical Society (ACS)},

month = {nov},

url = {https://doi.org/10.1021/la0520029},

number = {1},

pages = {2--5},

doi = {10.1021/la0520029}

}

MLA

Cite this

MLA Copy

Takahashi, Hironobu, et al. “Modification of Gold Nanorods Using Phosphatidylcholine to Reduce Cytotoxicity.” Langmuir, vol. 22, no. 1, Nov. 2005, pp. 2-5. https://doi.org/10.1021/la0520029.

Publisher

American Chemical Society (ACS)

Journal

Langmuir

scimago Q1

wos Q2

SJR

0.763

CiteScore

6.0

Impact factor

3.9

ISSN

07437463 (Print)

15205827 (Electronic)