ACS Nano, volume 6, issue 5, pages 3695-3702
Ag2S Quantum Dot: A Bright and Biocompatible Fluorescent Nanoprobe in the Second Near-Infrared Window
Publication type: Journal Article
Publication date: 2012-04-27
PubMed ID:
22515909
General Physics and Astronomy
General Materials Science
General Engineering
Abstract
Ag(2)S quantum dots (QDs) emitting in the second near-infrared region (NIR-II, 1.0-1.4 μm) are demonstrated as a promising fluorescent probe with both bright photoluminescence and high biocompatibility for the first time. Highly selective in vitro targeting and imaging of different cell lines are achieved using biocompatible NIR-II Ag(2)S QDs with different targeting ligands. The cytotoxicity study illustrates the Ag(2)S QDs with negligible effects in altering cell proliferation, triggering apoptosis and necrosis, generating reactive oxygen species, and causing DNA damage. Our results have opened up the possibilities of using these biocompatible Ag(2)S QDs for in vivo anatomical imaging and early stage tumor diagnosis with deep tissue penetration, high sensitivity, and elevated spatial and temporal resolution owing to their high emission efficiency in the unique NIR-II imaging window.
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Zhang Y. et al. Ag2S Quantum Dot: A Bright and Biocompatible Fluorescent Nanoprobe in the Second Near-Infrared Window // ACS Nano. 2012. Vol. 6. No. 5. pp. 3695-3702.
GOST all authors (up to 50)
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Zhang Y., Hong G., Zhang Y., Chen G., Li F., Dai H., Wang Q. Ag2S Quantum Dot: A Bright and Biocompatible Fluorescent Nanoprobe in the Second Near-Infrared Window // ACS Nano. 2012. Vol. 6. No. 5. pp. 3695-3702.
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TY - JOUR
DO - 10.1021/nn301218z
UR - https://doi.org/10.1021/nn301218z
TI - Ag2S Quantum Dot: A Bright and Biocompatible Fluorescent Nanoprobe in the Second Near-Infrared Window
T2 - ACS Nano
AU - Zhang, Yan
AU - Hong, Guosong
AU - Zhang, Yejun
AU - Chen, Guangcun
AU - Li, Feng
AU - Dai, Hongjie
AU - Wang, Qiangbin
PY - 2012
DA - 2012/04/27
PB - American Chemical Society (ACS)
SP - 3695-3702
IS - 5
VL - 6
PMID - 22515909
SN - 1936-0851
SN - 1936-086X
ER -
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BibTex (up to 50 authors)
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@article{2012_Zhang,
author = {Yan Zhang and Guosong Hong and Yejun Zhang and Guangcun Chen and Feng Li and Hongjie Dai and Qiangbin Wang},
title = {Ag2S Quantum Dot: A Bright and Biocompatible Fluorescent Nanoprobe in the Second Near-Infrared Window},
journal = {ACS Nano},
year = {2012},
volume = {6},
publisher = {American Chemical Society (ACS)},
month = {apr},
url = {https://doi.org/10.1021/nn301218z},
number = {5},
pages = {3695--3702},
doi = {10.1021/nn301218z}
}
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MLA
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Zhang, Yan, et al. “Ag2S Quantum Dot: A Bright and Biocompatible Fluorescent Nanoprobe in the Second Near-Infrared Window.” ACS Nano, vol. 6, no. 5, Apr. 2012, pp. 3695-3702. https://doi.org/10.1021/nn301218z.