New 9-Thiocyanatopupukeanane Sesquiterpenes from the Nudibranch Phyllidia varicosa and Its Sponge-Prey Axinyssa aculeata
Publication type: Journal Article
Publication date: 2003-10-30
scimago Q1
wos Q1
SJR: 0.629
CiteScore: 6.5
Impact factor: 3.6
ISSN: 01633864, 15206025
PubMed ID:
14640531
Organic Chemistry
Drug Discovery
Pharmacology
Pharmaceutical Science
Molecular Medicine
Complementary and alternative medicine
Analytical Chemistry
Abstract
Two new 9-thiocyanatopupukeanane sesquiterpene isomers were isolated as major metabolites from the MeOH extract of the sponge Axinyssa aculeata and from its nudibranch predator Phyllidia varicosa. The presence of the sesquiterpenes was monitored by GC−MS, and the structures were confirmed by both 1D and 2D NMR spectroscopy. The isolated sesquiterpenes were found to be toxic toward brine shrimp at LC50 of 5 ppm. At a dose level of 20 μg, they were found to be weakly and moderately active against B. subtilis and C. albicans, respectively.
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130
Total citations:
130
Citations from 2025:
10
(7.69%)
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GOST
Copy
Yasman et al. New 9-Thiocyanatopupukeanane Sesquiterpenes from the Nudibranch Phyllidia varicosa and Its Sponge-Prey Axinyssa aculeata // Journal of Natural Products. 2003. Vol. 66. No. 11. pp. 1512-1514.
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Yasman, Edrada R. A., Wray V., Proksch P. New 9-Thiocyanatopupukeanane Sesquiterpenes from the Nudibranch Phyllidia varicosa and Its Sponge-Prey Axinyssa aculeata // Journal of Natural Products. 2003. Vol. 66. No. 11. pp. 1512-1514.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/np030237j
UR - https://doi.org/10.1021/np030237j
TI - New 9-Thiocyanatopupukeanane Sesquiterpenes from the Nudibranch Phyllidia varicosa and Its Sponge-Prey Axinyssa aculeata
T2 - Journal of Natural Products
AU - Yasman
AU - Edrada, Ru Angelie
AU - Wray, Victor
AU - Proksch, Peter
PY - 2003
DA - 2003/10/30
PB - American Chemical Society (ACS)
SP - 1512-1514
IS - 11
VL - 66
PMID - 14640531
SN - 0163-3864
SN - 1520-6025
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2003_Yasman,
author = {Yasman and Ru Angelie Edrada and Victor Wray and Peter Proksch},
title = {New 9-Thiocyanatopupukeanane Sesquiterpenes from the Nudibranch Phyllidia varicosa and Its Sponge-Prey Axinyssa aculeata},
journal = {Journal of Natural Products},
year = {2003},
volume = {66},
publisher = {American Chemical Society (ACS)},
month = {oct},
url = {https://doi.org/10.1021/np030237j},
number = {11},
pages = {1512--1514},
doi = {10.1021/np030237j}
}
Cite this
MLA
Copy
Yasman, et al. “New 9-Thiocyanatopupukeanane Sesquiterpenes from the Nudibranch Phyllidia varicosa and Its Sponge-Prey Axinyssa aculeata.” Journal of Natural Products, vol. 66, no. 11, Oct. 2003, pp. 1512-1514. https://doi.org/10.1021/np030237j.