volume 69 issue 10 pages 1485-1487

Phenolic Marine Natural Products as Aldose Reductase Inhibitors

Publication typeJournal Article
Publication date2006-10-01
scimago Q1
wos Q1
SJR0.629
CiteScore6.5
Impact factor3.6
ISSN01633864, 15206025
PubMed ID:  17067167
Organic Chemistry
Drug Discovery
Pharmacology
Pharmaceutical Science
Molecular Medicine
Complementary and alternative medicine
Analytical Chemistry
Abstract
Four different types of marine natural compounds isolated from tunicates were found to inhibit human aldose reductase. They all are characterized by a heterocyclic system, and at least two phenolic groups are present in the structure. Two of the compounds tested showed an inhibitory potency 5/6-fold higher than that of the known AR inhibitor sorbinil. One notable structural feature of these active compounds is the lack of either the carboxylic acid or the spiro-hydantoin commonly present in the principal classes of currently used inhibitors.
Found 
Found 

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GOST |
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GOST Copy
Manzanaro S., Salvá J., De La Fuente J. Á. Phenolic Marine Natural Products as Aldose Reductase Inhibitors // Journal of Natural Products. 2006. Vol. 69. No. 10. pp. 1485-1487.
GOST all authors (up to 50) Copy
Manzanaro S., Salvá J., De La Fuente J. Á. Phenolic Marine Natural Products as Aldose Reductase Inhibitors // Journal of Natural Products. 2006. Vol. 69. No. 10. pp. 1485-1487.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/np0503698
UR - https://doi.org/10.1021/np0503698
TI - Phenolic Marine Natural Products as Aldose Reductase Inhibitors
T2 - Journal of Natural Products
AU - Manzanaro, Sonia
AU - Salvá, Javier
AU - De La Fuente, Jesús Ángel
PY - 2006
DA - 2006/10/01
PB - American Chemical Society (ACS)
SP - 1485-1487
IS - 10
VL - 69
PMID - 17067167
SN - 0163-3864
SN - 1520-6025
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2006_Manzanaro,
author = {Sonia Manzanaro and Javier Salvá and Jesús Ángel De La Fuente},
title = {Phenolic Marine Natural Products as Aldose Reductase Inhibitors},
journal = {Journal of Natural Products},
year = {2006},
volume = {69},
publisher = {American Chemical Society (ACS)},
month = {oct},
url = {https://doi.org/10.1021/np0503698},
number = {10},
pages = {1485--1487},
doi = {10.1021/np0503698}
}
MLA
Cite this
MLA Copy
Manzanaro, Sonia, et al. “Phenolic Marine Natural Products as Aldose Reductase Inhibitors.” Journal of Natural Products, vol. 69, no. 10, Oct. 2006, pp. 1485-1487. https://doi.org/10.1021/np0503698.