Iterative Organometallic Addition to Chiral Hydroxylated Cyclic Nitrones: Highly Stereoselective Syntheses of α,α‘- and α,α-Substituted Hydroxypyrrolidines
Тип публикации: Journal Article
Дата публикации: 2003-10-01
SCImago Q1
Tоп 10% SCImago
WOS Q1
БС1
SJR: 1.007
CiteScore: 7.7
Impact factor: 4.7
ISSN: 15237060, 15237052
PubMed ID:
14572293
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Краткое описание
Iteration of organometallic addition to chiral hydroxylated pyrroline N-oxides through an addition-oxidation-addition synthetic sequence allowed highly stereoselective double alkylation of pyrrolidine at C-2 or at C-2 and C-5 depending on the regioselectivity of the oxidation step. Application of this methodology has been exemplified by the synthesis of the all-substituted pyrrolidine alkaloid (−)-codonopsinine and of proline-type amino acid precursors possessing a quaternary stereogenic center, whose configuration can be controlled.
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ГОСТ
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Goti A. et al. Iterative Organometallic Addition to Chiral Hydroxylated Cyclic Nitrones: Highly Stereoselective Syntheses of α,α‘- and α,α-Substituted Hydroxypyrrolidines // Organic Letters. 2003. Vol. 5. No. 22. pp. 4235-4238.
ГОСТ со всеми авторами (до 50)
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Goti A., Cicchi S., Mannucci V., Cardona F., Guarna F., Merino P., Tejero T. Iterative Organometallic Addition to Chiral Hydroxylated Cyclic Nitrones: Highly Stereoselective Syntheses of α,α‘- and α,α-Substituted Hydroxypyrrolidines // Organic Letters. 2003. Vol. 5. No. 22. pp. 4235-4238.
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RIS
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TY - JOUR
DO - 10.1021/ol035798g
UR - https://doi.org/10.1021/ol035798g
TI - Iterative Organometallic Addition to Chiral Hydroxylated Cyclic Nitrones: Highly Stereoselective Syntheses of α,α‘- and α,α-Substituted Hydroxypyrrolidines
T2 - Organic Letters
AU - Goti, A.
AU - Cicchi, Stefano
AU - Mannucci, Vanni
AU - Cardona, Francesca
AU - Guarna, Francesco
AU - Merino, Pedro
AU - Tejero, T.
PY - 2003
DA - 2003/10/01
PB - American Chemical Society (ACS)
SP - 4235-4238
IS - 22
VL - 5
PMID - 14572293
SN - 1523-7060
SN - 1523-7052
ER -
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BibTex (до 50 авторов)
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@article{2003_Goti,
author = {A. Goti and Stefano Cicchi and Vanni Mannucci and Francesca Cardona and Francesco Guarna and Pedro Merino and T. Tejero},
title = {Iterative Organometallic Addition to Chiral Hydroxylated Cyclic Nitrones: Highly Stereoselective Syntheses of α,α‘- and α,α-Substituted Hydroxypyrrolidines},
journal = {Organic Letters},
year = {2003},
volume = {5},
publisher = {American Chemical Society (ACS)},
month = {oct},
url = {https://doi.org/10.1021/ol035798g},
number = {22},
pages = {4235--4238},
doi = {10.1021/ol035798g}
}
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MLA
Скопировать
Goti, A., et al. “Iterative Organometallic Addition to Chiral Hydroxylated Cyclic Nitrones: Highly Stereoselective Syntheses of α,α‘- and α,α-Substituted Hydroxypyrrolidines.” Organic Letters, vol. 5, no. 22, Oct. 2003, pp. 4235-4238. https://doi.org/10.1021/ol035798g.
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