Direct C2-Alkylation of Azoles with Alcohols and Ethers through Dehydrogenative Cross-Coupling under Metal-Free Conditions
Тип публикации: Journal Article
Дата публикации: 2011-08-29
scimago Q1
wos Q1
БС1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
21875038
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Краткое описание
A metal-free novel, simple, and highly efficient method for the direct C2-alkylation of azoles with alcohols and ethers has been developed on the basis of an oxidative C–H activation process. The dehydrogenative C–C cross-coupling reactions of α-position sp3 C–H in alcohols and ethers with the 2-position sp2 C–H in azoles proceeded smoothly in the presence of tert-butyl hydroperoxide (TBHP) under neat reaction conditions, which generated the corresponding products in good yields.
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ГОСТ |
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MLA
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ГОСТ
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He T. et al. Direct C2-Alkylation of Azoles with Alcohols and Ethers through Dehydrogenative Cross-Coupling under Metal-Free Conditions // Organic Letters. 2011. Vol. 13. No. 19. pp. 5016-5019.
ГОСТ со всеми авторами (до 50)
Скопировать
He T., Lin Yu., Zhang L., Wang L., Wang M. Direct C2-Alkylation of Azoles with Alcohols and Ethers through Dehydrogenative Cross-Coupling under Metal-Free Conditions // Organic Letters. 2011. Vol. 13. No. 19. pp. 5016-5019.
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RIS
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TY - JOUR
DO - 10.1021/ol201779n
UR - https://doi.org/10.1021/ol201779n
TI - Direct C2-Alkylation of Azoles with Alcohols and Ethers through Dehydrogenative Cross-Coupling under Metal-Free Conditions
T2 - Organic Letters
AU - He, Tao
AU - Lin, Yu
AU - Zhang, Lei
AU - Wang, Lei
AU - Wang, Min
PY - 2011
DA - 2011/08/29
PB - American Chemical Society (ACS)
SP - 5016-5019
IS - 19
VL - 13
PMID - 21875038
SN - 1523-7060
SN - 1523-7052
ER -
Цитировать
BibTex (до 50 авторов)
Скопировать
@article{2011_He,
author = {Tao He and Yu Lin and Lei Zhang and Lei Wang and Min Wang},
title = {Direct C2-Alkylation of Azoles with Alcohols and Ethers through Dehydrogenative Cross-Coupling under Metal-Free Conditions},
journal = {Organic Letters},
year = {2011},
volume = {13},
publisher = {American Chemical Society (ACS)},
month = {aug},
url = {https://doi.org/10.1021/ol201779n},
number = {19},
pages = {5016--5019},
doi = {10.1021/ol201779n}
}
Цитировать
MLA
Скопировать
He, Tao, et al. “Direct C2-Alkylation of Azoles with Alcohols and Ethers through Dehydrogenative Cross-Coupling under Metal-Free Conditions.” Organic Letters, vol. 13, no. 19, Aug. 2011, pp. 5016-5019. https://doi.org/10.1021/ol201779n.