Organic Letters, volume 14, issue 20, pages 5196-5199
[5C + 1N] Annulations: Two Novel Routes to Substituted Dihydrofuro[3,2-c]pyridines
Publication type: Journal Article
Publication date: 2012-10-01
Journal:
Organic Letters
Q1
Q1
SJR: 1.245
CiteScore: 9.3
Impact factor: 4.9
ISSN: 15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
Two novel routes based on [5C + 1N] annulations for the synthesis of 2,3-dihydrofuro[3,2-c]pyridines are described. Ammonium acetate (NH(4)OAc) is used as an ammonia source in both routes. The first route utilizes 1-acyl-1-[(dimethylamino)alkenoyl]cyclopropanes as a five-carbon 1,5-bielectrophilic species and combines the [5C + 1N] annulation and regioselective ring-enlargement of cyclopropyl ketone into one pot, whereas the second route utilizes 3-acyl-2-[(dimethylamino)alkenyl]-4,5-dihydrofurans as the five-carbon synthons, which involves a sequential intermolecular aza-addition, intramolecular aza-nucleophilic addition/elimination, and dehydration reaction.
Found
Found
Top-30
Journals
|
1
2
3
4
|
|
|
Journal of Organic Chemistry
4 publications, 14.81%
|
|
|
Tetrahedron
2 publications, 7.41%
|
|
|
Advanced Synthesis and Catalysis
2 publications, 7.41%
|
|
|
Organic Letters
2 publications, 7.41%
|
|
|
Organic Chemistry Frontiers
2 publications, 7.41%
|
|
|
RSC Advances
2 publications, 7.41%
|
|
|
Israel Journal of Chemistry
1 publication, 3.7%
|
|
|
European Journal of Organic Chemistry
1 publication, 3.7%
|
|
|
Chemistry - A European Journal
1 publication, 3.7%
|
|
|
ChemistrySelect
1 publication, 3.7%
|
|
|
ChemInform
1 publication, 3.7%
|
|
|
Journal of the American Chemical Society
1 publication, 3.7%
|
|
|
ACS Omega
1 publication, 3.7%
|
|
|
Chemical Communications
1 publication, 3.7%
|
|
|
Chemical Science
1 publication, 3.7%
|
|
|
Green Chemistry
1 publication, 3.7%
|
|
|
Dalton Transactions
1 publication, 3.7%
|
|
|
Progress in Heterocyclic Chemistry
1 publication, 3.7%
|
|
|
Russian Chemical Reviews
1 publication, 3.7%
|
|
|
1
2
3
4
|
Publishers
|
1
2
3
4
5
6
7
8
|
|
|
American Chemical Society (ACS)
8 publications, 29.63%
|
|
|
Royal Society of Chemistry (RSC)
8 publications, 29.63%
|
|
|
Wiley
7 publications, 25.93%
|
|
|
Elsevier
3 publications, 11.11%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 3.7%
|
|
|
1
2
3
4
5
6
7
8
|
- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Huang P. et al. [5C + 1N] Annulations: Two Novel Routes to Substituted Dihydrofuro[3,2-c]pyridines // Organic Letters. 2012. Vol. 14. No. 20. pp. 5196-5199.
GOST all authors (up to 50)
Copy
Huang P., Zhang R., Liang Y., Dong D. [5C + 1N] Annulations: Two Novel Routes to Substituted Dihydrofuro[3,2-c]pyridines // Organic Letters. 2012. Vol. 14. No. 20. pp. 5196-5199.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/ol302314c
UR - https://doi.org/10.1021/ol302314c
TI - [5C + 1N] Annulations: Two Novel Routes to Substituted Dihydrofuro[3,2-c]pyridines
T2 - Organic Letters
AU - Huang, Peng
AU - Zhang, Rui
AU - Liang, Yongjiu
AU - Dong, Dewen
PY - 2012
DA - 2012/10/01
PB - American Chemical Society (ACS)
SP - 5196-5199
IS - 20
VL - 14
SN - 1523-7060
SN - 1523-7052
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2012_Huang,
author = {Peng Huang and Rui Zhang and Yongjiu Liang and Dewen Dong},
title = {[5C + 1N] Annulations: Two Novel Routes to Substituted Dihydrofuro[3,2-c]pyridines},
journal = {Organic Letters},
year = {2012},
volume = {14},
publisher = {American Chemical Society (ACS)},
month = {oct},
url = {https://doi.org/10.1021/ol302314c},
number = {20},
pages = {5196--5199},
doi = {10.1021/ol302314c}
}
Cite this
MLA
Copy
Huang, Peng, et al. “[5C + 1N] Annulations: Two Novel Routes to Substituted Dihydrofuro[3,2-c]pyridines.” Organic Letters, vol. 14, no. 20, Oct. 2012, pp. 5196-5199. https://doi.org/10.1021/ol302314c.