Organic Letters

, volume 9 , issue 21 , pages 4295-4298

Enantioselective Pd-Catalyzed Allylic Alkylation of Indoles by a New Class of Chiral Ferrocenyl P/S Ligands

Hong Yee Cheung ¹

W. X. Yu ¹

Fuk Loi Lam ¹

Terry T.-L. Au-Yeung ¹

Zhongyuan Zhou ¹

Tak Hang Chan ¹

Albert S. Chan ¹

Hide authors affiliations Show authors affiliations: 1 affiliation

Open Laboratory of Chirotechnology of the Institute of Molecular Technology for Drug Discovery and Synthesis, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong |

Publication type: Journal Article

Publication date: 2007-09-13

American Chemical Society (ACS)

Organic Letters

scimago Q1

wos Q1

SJR: 1.235

CiteScore: 8.7

Impact factor: 5.0

ISSN: 15237060, 15237052

DOI: 10.1021/ol7018532

Copy DOI

PubMed ID: 17850156

Organic Chemistry

Biochemistry

Physical and Theoretical Chemistry

Abstract

Chiral ferrocenyl heterobidentate P/S ligands bearing both central and planar chirality were prepared from (S)-Ugi's amine via a three-step modular synthesis. Through systematic screening and optimization, L8 was found to be the best ligand for Pd-catalyzed asymmetric allylic alkylation of indoles with ee's up to 96% being attained.

Found

2 citations

Gavrilov Konstantin

DSc in Chemistry, professor

149 publications, 1 766 citations

h-index: 20

Ryazan State University named after S. A. Esenin

Research interests

Asymmetric metal complex catalysis

Asymmetric synthesis

Complex formation

2 citations

Zamilatskov Ilya

🥼 🤝

PhD in Chemistry

64 publications, 470 citations

h-index: 11

A.N. Frumkin Institute of Physical Chemistry and Electrochemistry of the Russian Academy of Sciences

Research interests

Organic Chemistry

1 citation

Tyurin Vladimir

🥼 🤝

PhD in Chemistry

71 publications, 1 818 citations, 7 reviews

h-index: 15

A.N. Frumkin Institute of Physical Chemistry and Electrochemistry of the Russian Academy of Sciences

Supramolecular chemistry

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GOST |

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GOST Copy

Cheung H. Y. et al. Enantioselective Pd-Catalyzed Allylic Alkylation of Indoles by a New Class of Chiral Ferrocenyl P/S Ligands // Organic Letters. 2007. Vol. 9. No. 21. pp. 4295-4298.

GOST all authors (up to 50) Copy

Cheung H. Y., Yu W. X., Lam F. L., Au-Yeung T. T., Zhou Z., Chan T. H., Chan A. S. Enantioselective Pd-Catalyzed Allylic Alkylation of Indoles by a New Class of Chiral Ferrocenyl P/S Ligands // Organic Letters. 2007. Vol. 9. No. 21. pp. 4295-4298.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1021/ol7018532

UR - https://doi.org/10.1021/ol7018532

TI - Enantioselective Pd-Catalyzed Allylic Alkylation of Indoles by a New Class of Chiral Ferrocenyl P/S Ligands

T2 - Organic Letters

AU - Cheung, Hong Yee

AU - Yu, W. X.

AU - Lam, Fuk Loi

AU - Au-Yeung, Terry T.-L.

AU - Zhou, Zhongyuan

AU - Chan, Tak Hang

AU - Chan, Albert S.

PY - 2007

DA - 2007/09/13

PB - American Chemical Society (ACS)

SP - 4295-4298

IS - 21

VL - 9

PMID - 17850156

SN - 1523-7060

SN - 1523-7052

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2007_Cheung,

author = {Hong Yee Cheung and W. X. Yu and Fuk Loi Lam and Terry T.-L. Au-Yeung and Zhongyuan Zhou and Tak Hang Chan and Albert S. Chan},

title = {Enantioselective Pd-Catalyzed Allylic Alkylation of Indoles by a New Class of Chiral Ferrocenyl P/S Ligands},

journal = {Organic Letters},

year = {2007},

volume = {9},

publisher = {American Chemical Society (ACS)},

month = {sep},

url = {https://doi.org/10.1021/ol7018532},

number = {21},

pages = {4295--4298},

doi = {10.1021/ol7018532}

}

MLA

Cite this

MLA Copy

Cheung, Hong Yee, et al. “Enantioselective Pd-Catalyzed Allylic Alkylation of Indoles by a New Class of Chiral Ferrocenyl P/S Ligands.” Organic Letters, vol. 9, no. 21, Sep. 2007, pp. 4295-4298. https://doi.org/10.1021/ol7018532.

Publisher

American Chemical Society (ACS)

Journal

Organic Letters

scimago Q1

wos Q1

SJR

1.235

CiteScore

8.7

Impact factor

5.0

ISSN

15237060 (Print)

15237052 (Electronic)