Nature Methods, volume 14, issue 6, pages 587-589
ModelFinder: fast model selection for accurate phylogenetic estimates
Subha Kalyaanamoorthy
1, 2
,
Bui Quang Minh
3
,
THOMAS K. F. WONG
1, 4
,
Arndt von Haeseler
3, 5
,
Lars S Jermiin
1, 4
Publication type: Journal Article
Publication date: 2017-05-08
Journal:
Nature Methods
scimago Q1
SJR: 14.796
CiteScore: 58.7
Impact factor: 36.1
ISSN: 15487091, 15487105
PubMed ID:
28481363
Biochemistry
Molecular Biology
Cell Biology
Biotechnology
Abstract
ModelFinder is a fast model-selection method that greatly improves the accuracy of phylogenetic estimates. Model-based molecular phylogenetics plays an important role in comparisons of genomic data, and model selection is a key step in all such analyses. We present ModelFinder, a fast model-selection method that greatly improves the accuracy of phylogenetic estimates by incorporating a model of rate heterogeneity across sites not previously considered in this context and by allowing concurrent searches of model space and tree space.
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