Antidepressants in inflammatory bowel disease
3
Leeds Gastroenterology Institute, St James’s University Hospital, Leeds, UK
|
5
Center for Education and Practice of Biopsychosocial Care and Drossman Gastroenterology, Chapel Hill, USA
|
Publication type: Journal Article
Publication date: 2020-02-18
scimago Q1
wos Q1
SJR: 9.911
CiteScore: 58.7
Impact factor: 51.0
ISSN: 17595045, 17595053
PubMed ID:
32071420
Gastroenterology
Hepatology
Abstract
Gut–brain dysregulation has been recognized by the scientific community as being crucial to the understanding of chronic gastrointestinal conditions, and this has translated into the practice of a newly established discipline, psychogastroenterology. Along with psychotherapy, antidepressants (a subtype of central neuromodulators) have been proposed as treatments for gut–brain disorders that might benefit both psychological and gastrointestinal health. Antidepressants have been found to be effective for the treatment of comorbid anxiety and depression, pain and impaired sleep. Although the efficacy of antidepressants is well established in disorders of gut–brain interaction (DGBI), evidence is only now emerging in IBD. This Perspective discusses the use of antidepressants in DGBI and IBD, focusing on how what we have learnt about the role of antidepressants in DGBI could be applied to help optimize the management of IBD. This Perspective discusses the use of antidepressants in disorders of gut–brain interaction (DGBI) and IBD, focusing on how what we have learnt about the role of antidepressants in DGBI could help optimize the management of IBD.
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72
Total citations:
72
Citations from 2024:
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(40.28%)
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GOST
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Mikocka-Walus A. A. et al. Antidepressants in inflammatory bowel disease // Nature Reviews Gastroenterology and Hepatology. 2020. Vol. 17. No. 3. pp. 184-192.
GOST all authors (up to 50)
Copy
Mikocka-Walus A. A., Ford A. J., Drossman D. A. Antidepressants in inflammatory bowel disease // Nature Reviews Gastroenterology and Hepatology. 2020. Vol. 17. No. 3. pp. 184-192.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1038/s41575-019-0259-y
UR - https://doi.org/10.1038/s41575-019-0259-y
TI - Antidepressants in inflammatory bowel disease
T2 - Nature Reviews Gastroenterology and Hepatology
AU - Mikocka-Walus, Antonina A
AU - Ford, A. J.
AU - Drossman, Douglas A
PY - 2020
DA - 2020/02/18
PB - Springer Nature
SP - 184-192
IS - 3
VL - 17
PMID - 32071420
SN - 1759-5045
SN - 1759-5053
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2020_Mikocka-Walus,
author = {Antonina A Mikocka-Walus and A. J. Ford and Douglas A Drossman},
title = {Antidepressants in inflammatory bowel disease},
journal = {Nature Reviews Gastroenterology and Hepatology},
year = {2020},
volume = {17},
publisher = {Springer Nature},
month = {feb},
url = {https://doi.org/10.1038/s41575-019-0259-y},
number = {3},
pages = {184--192},
doi = {10.1038/s41575-019-0259-y}
}
Cite this
MLA
Copy
Mikocka-Walus, Antonina A., et al. “Antidepressants in inflammatory bowel disease.” Nature Reviews Gastroenterology and Hepatology, vol. 17, no. 3, Feb. 2020, pp. 184-192. https://doi.org/10.1038/s41575-019-0259-y.