Molecular mechanisms of antibiotic resistance
Publication type: Journal Article
Publication date: 2014-12-01
scimago Q1
wos Q1
SJR: 13.861
CiteScore: 106.4
Impact factor: 103.3
ISSN: 17401526, 17401534
PubMed ID:
25435309
Microbiology
Infectious Diseases
General Immunology and Microbiology
Abstract
Antibiotic-resistant bacteria that are difficult or impossible to treat are becoming increasingly common and are causing a global health crisis. Antibiotic resistance is encoded by several genes, many of which can transfer between bacteria. New resistance mechanisms are constantly being described, and new genes and vectors of transmission are identified on a regular basis. This article reviews recent advances in our understanding of the mechanisms by which bacteria are either intrinsically resistant or acquire resistance to antibiotics, including the prevention of access to drug targets, changes in the structure and protection of antibiotic targets and the direct modification or inactivation of antibiotics.
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GOST
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Blair J. M. A. et al. Molecular mechanisms of antibiotic resistance // Nature Reviews Microbiology. 2014. Vol. 13. No. 1. pp. 42-51.
GOST all authors (up to 50)
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Blair J. M. A., Webber M. A., Baylay A. J., Ogbolu D. O., Piddock L. J. Molecular mechanisms of antibiotic resistance // Nature Reviews Microbiology. 2014. Vol. 13. No. 1. pp. 42-51.
Cite this
RIS
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TY - JOUR
DO - 10.1038/nrmicro3380
UR - https://doi.org/10.1038/nrmicro3380
TI - Molecular mechanisms of antibiotic resistance
T2 - Nature Reviews Microbiology
AU - Blair, Jessica M. A.
AU - Webber, Mark A.
AU - Baylay, Alison J
AU - Ogbolu, David O
AU - Piddock, Laura J. V.
PY - 2014
DA - 2014/12/01
PB - Springer Nature
SP - 42-51
IS - 1
VL - 13
PMID - 25435309
SN - 1740-1526
SN - 1740-1534
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2014_Blair,
author = {Jessica M. A. Blair and Mark A. Webber and Alison J Baylay and David O Ogbolu and Laura J. V. Piddock},
title = {Molecular mechanisms of antibiotic resistance},
journal = {Nature Reviews Microbiology},
year = {2014},
volume = {13},
publisher = {Springer Nature},
month = {dec},
url = {https://doi.org/10.1038/nrmicro3380},
number = {1},
pages = {42--51},
doi = {10.1038/nrmicro3380}
}
Cite this
MLA
Copy
Blair, Jessica M. A., et al. “Molecular mechanisms of antibiotic resistance.” Nature Reviews Microbiology, vol. 13, no. 1, Dec. 2014, pp. 42-51. https://doi.org/10.1038/nrmicro3380.