Determination of ethinyloestradiol in single tablets and its separation from other steroids by high-performance liquid chromatography
Publication type: Journal Article
Publication date: 1978-01-01
scimago Q2
wos Q2
SJR: 0.617
CiteScore: 7.0
Impact factor: 3.3
ISSN: 00032654, 13645528, 07417918
PubMed ID:
637304
Biochemistry
Spectroscopy
Analytical Chemistry
Electrochemistry
Environmental Chemistry
Abstract
A reversed-phase chromatographic system is used to separate 17α-ethinyloestradiol-1,3,5(10)-triene-3,17β-diol (ethinyloestradiol) from structurally related steroidal compounds. A direct and highly sensitive method of assay is given for uncoated tablets containing ethinyloestradiol, as used for contraception. The method is modified for sugar-coated tablets used for relief of menopause symptoms and is sufficiently sensitive to detect ethinyloestradiol if it is present with other steroids as a contaminant.
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17
Total citations:
17
Citations from 2024:
0
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GOST
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Bagon K. R., Hammond E. W. Determination of ethinyloestradiol in single tablets and its separation from other steroids by high-performance liquid chromatography // The Analyst. 1978. Vol. 103. No. 1223. p. 156.
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Bagon K. R., Hammond E. W. Determination of ethinyloestradiol in single tablets and its separation from other steroids by high-performance liquid chromatography // The Analyst. 1978. Vol. 103. No. 1223. p. 156.
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RIS
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TY - JOUR
DO - 10.1039/an9780300156
UR - https://doi.org/10.1039/an9780300156
TI - Determination of ethinyloestradiol in single tablets and its separation from other steroids by high-performance liquid chromatography
T2 - The Analyst
AU - Bagon, Kay R
AU - Hammond, E W
PY - 1978
DA - 1978/01/01
PB - Royal Society of Chemistry (RSC)
SP - 156
IS - 1223
VL - 103
PMID - 637304
SN - 0003-2654
SN - 1364-5528
SN - 0741-7918
ER -
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BibTex (up to 50 authors)
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@article{1978_Bagon,
author = {Kay R Bagon and E W Hammond},
title = {Determination of ethinyloestradiol in single tablets and its separation from other steroids by high-performance liquid chromatography},
journal = {The Analyst},
year = {1978},
volume = {103},
publisher = {Royal Society of Chemistry (RSC)},
month = {jan},
url = {https://doi.org/10.1039/an9780300156},
number = {1223},
pages = {156},
doi = {10.1039/an9780300156}
}
Cite this
MLA
Copy
Bagon, Kay R., and E W Hammond. “Determination of ethinyloestradiol in single tablets and its separation from other steroids by high-performance liquid chromatography.” The Analyst, vol. 103, no. 1223, Jan. 1978, p. 156. https://doi.org/10.1039/an9780300156.