Synthesis and full characterisation of 6-chloro-2-iodopurine, a template for the functionalisation of purines
Publication type: Journal Article
Publication date: 2004-02-25
scimago Q2
wos Q2
SJR: 0.600
CiteScore: 5.2
Impact factor: 2.7
ISSN: 14770520, 14770539
DOI:
10.1039/b312629c
PubMed ID:
14985806
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A simple and efficient synthesis of 6-chloro-2-iodopurine from hypoxanthine has been achieved. This strategy relied on a regiospecific lithiation/quenching sequence of 6-chloro-9-(tetrahydropyran-2-yl)purine using Harpoon's base and tributyltin chloride. HMBC NMR studies on the product and intermediates confirmed the regioselectivity of this methodology. The molecular structures of the final dihalogenopurine and its 9-protected precursor were determined by single crystal X-ray diffraction.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
4
|
|
|
Journal of Medicinal Chemistry
4 publications, 19.05%
|
|
|
Tetrahedron
2 publications, 9.52%
|
|
|
Annual Reports on NMR Spectroscopy
2 publications, 9.52%
|
|
|
Acta Crystallographica Section E Structure Reports Online
1 publication, 4.76%
|
|
|
Royal Society Open Science
1 publication, 4.76%
|
|
|
Biomolecules
1 publication, 4.76%
|
|
|
International Journal of Molecular Sciences
1 publication, 4.76%
|
|
|
Bioorganic Chemistry
1 publication, 4.76%
|
|
|
Bioorganic and Medicinal Chemistry
1 publication, 4.76%
|
|
|
Phytochemistry
1 publication, 4.76%
|
|
|
Arabian Journal of Chemistry
1 publication, 4.76%
|
|
|
European Journal of Organic Chemistry
1 publication, 4.76%
|
|
|
Chemical Reviews
1 publication, 4.76%
|
|
|
European Journal of Medicinal Chemistry
1 publication, 4.76%
|
|
|
ChemistrySelect
1 publication, 4.76%
|
|
|
1
2
3
4
|
Publishers
|
1
2
3
4
5
6
7
8
9
|
|
|
Elsevier
9 publications, 42.86%
|
|
|
American Chemical Society (ACS)
5 publications, 23.81%
|
|
|
MDPI
2 publications, 9.52%
|
|
|
Wiley
2 publications, 9.52%
|
|
|
International Union of Crystallography (IUCr)
1 publication, 4.76%
|
|
|
The Royal Society
1 publication, 4.76%
|
|
|
King Saud University
1 publication, 4.76%
|
|
|
1
2
3
4
5
6
7
8
9
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
21
Total citations:
21
Citations from 2024:
2
(9%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Taddei D. et al. Synthesis and full characterisation of 6-chloro-2-iodopurine, a template for the functionalisation of purines // Organic and Biomolecular Chemistry. 2004. Vol. 2. No. 5. p. 665.
GOST all authors (up to 50)
Copy
Taddei D., Kilián P., Slawin A. M. Z., Woollins J. D. Synthesis and full characterisation of 6-chloro-2-iodopurine, a template for the functionalisation of purines // Organic and Biomolecular Chemistry. 2004. Vol. 2. No. 5. p. 665.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1039/b312629c
UR - https://doi.org/10.1039/b312629c
TI - Synthesis and full characterisation of 6-chloro-2-iodopurine, a template for the functionalisation of purines
T2 - Organic and Biomolecular Chemistry
AU - Taddei, David
AU - Kilián, Petr
AU - Slawin, Alexandra M. Z.
AU - Woollins, J. Derek
PY - 2004
DA - 2004/02/25
PB - Royal Society of Chemistry (RSC)
SP - 665
IS - 5
VL - 2
PMID - 14985806
SN - 1477-0520
SN - 1477-0539
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2004_Taddei,
author = {David Taddei and Petr Kilián and Alexandra M. Z. Slawin and J. Derek Woollins},
title = {Synthesis and full characterisation of 6-chloro-2-iodopurine, a template for the functionalisation of purines},
journal = {Organic and Biomolecular Chemistry},
year = {2004},
volume = {2},
publisher = {Royal Society of Chemistry (RSC)},
month = {feb},
url = {https://doi.org/10.1039/b312629c},
number = {5},
pages = {665},
doi = {10.1039/b312629c}
}
Cite this
MLA
Copy
Taddei, David, et al. “Synthesis and full characterisation of 6-chloro-2-iodopurine, a template for the functionalisation of purines.” Organic and Biomolecular Chemistry, vol. 2, no. 5, Feb. 2004, p. 665. https://doi.org/10.1039/b312629c.
Profiles