Direct sequential C-H iodination/organoyl-thiolation for the benzenoid A-ring modification of quinonoid deactivated systems: a new protocol for potent trypanocidal quinones.
Тип публикации: Journal Article
Дата публикации: 2018-02-08
scimago Q2
wos Q2
БС1
SJR: 0.600
CiteScore: 5.2
Impact factor: 2.7
ISSN: 14770520, 14770539
PubMed ID:
29450434
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Краткое описание
We report a sequential C-H iodination/organoyl-thiolation of naphthoquinones and their relevant trypanocidal activity. Under a combination of AgSR with a copper source, sulfur-substituted benzenoid quinones were prepared in high yields (generally >90%). This provides an efficient and general method for preparing A-ring modified naphthoquinoidal systems, recognized as a challenge in quinone chemistry.
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ГОСТ
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Jardim G. A. et al. Direct sequential C-H iodination/organoyl-thiolation for the benzenoid A-ring modification of quinonoid deactivated systems: a new protocol for potent trypanocidal quinones. // Organic and Biomolecular Chemistry. 2018. Vol. 16. No. 10. pp. 1686-1691.
ГОСТ со всеми авторами (до 50)
Скопировать
Jardim G. A., Oliveira W., Freitas R., Menna-Barreto R., Silva T., Goulart M. O., da Silva Júnior E. N. Direct sequential C-H iodination/organoyl-thiolation for the benzenoid A-ring modification of quinonoid deactivated systems: a new protocol for potent trypanocidal quinones. // Organic and Biomolecular Chemistry. 2018. Vol. 16. No. 10. pp. 1686-1691.
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RIS
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TY - JOUR
DO - 10.1039/C8OB00196K
UR - https://doi.org/10.1039/C8OB00196K
TI - Direct sequential C-H iodination/organoyl-thiolation for the benzenoid A-ring modification of quinonoid deactivated systems: a new protocol for potent trypanocidal quinones.
T2 - Organic and Biomolecular Chemistry
AU - Jardim, Guilherme A.M.
AU - Oliveira, Willian
AU - Freitas, Rossimiriam
AU - Menna-Barreto, Rubem F.S.
AU - Silva, Thaissa
AU - Goulart, Marilia O.
AU - da Silva Júnior, Eufrânio N.
PY - 2018
DA - 2018/02/08
PB - Royal Society of Chemistry (RSC)
SP - 1686-1691
IS - 10
VL - 16
PMID - 29450434
SN - 1477-0520
SN - 1477-0539
ER -
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BibTex (до 50 авторов)
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@article{2018_Jardim,
author = {Guilherme A.M. Jardim and Willian Oliveira and Rossimiriam Freitas and Rubem F.S. Menna-Barreto and Thaissa Silva and Marilia O. Goulart and Eufrânio N. da Silva Júnior},
title = {Direct sequential C-H iodination/organoyl-thiolation for the benzenoid A-ring modification of quinonoid deactivated systems: a new protocol for potent trypanocidal quinones.},
journal = {Organic and Biomolecular Chemistry},
year = {2018},
volume = {16},
publisher = {Royal Society of Chemistry (RSC)},
month = {feb},
url = {https://doi.org/10.1039/C8OB00196K},
number = {10},
pages = {1686--1691},
doi = {10.1039/C8OB00196K}
}
Цитировать
MLA
Скопировать
Jardim, Guilherme A.M., et al. “Direct sequential C-H iodination/organoyl-thiolation for the benzenoid A-ring modification of quinonoid deactivated systems: a new protocol for potent trypanocidal quinones..” Organic and Biomolecular Chemistry, vol. 16, no. 10, Feb. 2018, pp. 1686-1691. https://doi.org/10.1039/C8OB00196K.