Open Access
Nanoparticles and bioorthogonal chemistry joining forces for improved biomedical applications
Javier Idiago López
1, 2, 3, 4, 5, 6, 7
,
Eduardo Moreno Antolín
1, 3, 4, 5, 6
,
Jesús Grajal de la Fuente
1, 2, 3, 4, 5, 6, 7
,
Raluca M. Fratila
1, 2, 3, 4, 5, 6, 7
1
5
Zaragoza 50009
|
6
SPAIN
|
7
Centro de Investigación Biomédica en Red de Bioingeniería
Publication type: Journal Article
Publication date: 2021-01-21
scimago Q1
wos Q2
SJR: 0.974
CiteScore: 8.6
Impact factor: 4.6
ISSN: 25160230
PubMed ID:
36132873
General Chemistry
Atomic and Molecular Physics, and Optics
General Materials Science
Bioengineering
General Engineering
Abstract
Bioorthogonal chemistry comprises chemical reactions that can take place inside complex biological environments, providing outstanding tools for the investigation and elucidation of biological processes. Its use in combination with nanotechnology can lead to further developments in diverse areas of biomedicine, such as molecular bioimaging, targeted delivery, in situ drug activation, study of cell–nanomaterial interactions, biosensing, etc. Here, we summarise the recent efforts to bring together the unique properties of nanoparticles and the remarkable features of bioorthogonal reactions to create a toolbox of new or improved biomedical applications. We show how, by joining forces, bioorthogonal chemistry and nanotechnology can overcome some of the key current limitations in the field of nanomedicine, providing better, faster and more sensitive nanoparticle-based bioimaging and biosensing techniques, as well as therapeutic nanoplatforms with superior efficacy.
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44
Total citations:
44
Citations from 2024:
22
(50%)
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MLA
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GOST
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Idiago López J. et al. Nanoparticles and bioorthogonal chemistry joining forces for improved biomedical applications // Nanoscale Advances. 2021. Vol. 3. No. 5. pp. 1261-1292.
GOST all authors (up to 50)
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Idiago López J., Moreno Antolín E., de la Fuente J. G., Fratila R. M. Nanoparticles and bioorthogonal chemistry joining forces for improved biomedical applications // Nanoscale Advances. 2021. Vol. 3. No. 5. pp. 1261-1292.
Cite this
RIS
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TY - JOUR
DO - 10.1039/d0na00873g
UR - https://xlink.rsc.org/?DOI=D0NA00873G
TI - Nanoparticles and bioorthogonal chemistry joining forces for improved biomedical applications
T2 - Nanoscale Advances
AU - Idiago López, Javier
AU - Moreno Antolín, Eduardo
AU - de la Fuente, Jesús Grajal
AU - Fratila, Raluca M.
PY - 2021
DA - 2021/01/21
PB - Royal Society of Chemistry (RSC)
SP - 1261-1292
IS - 5
VL - 3
PMID - 36132873
SN - 2516-0230
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Idiago López,
author = {Javier Idiago López and Eduardo Moreno Antolín and Jesús Grajal de la Fuente and Raluca M. Fratila},
title = {Nanoparticles and bioorthogonal chemistry joining forces for improved biomedical applications},
journal = {Nanoscale Advances},
year = {2021},
volume = {3},
publisher = {Royal Society of Chemistry (RSC)},
month = {jan},
url = {https://xlink.rsc.org/?DOI=D0NA00873G},
number = {5},
pages = {1261--1292},
doi = {10.1039/d0na00873g}
}
Cite this
MLA
Copy
Idiago López, Javier, et al. “Nanoparticles and bioorthogonal chemistry joining forces for improved biomedical applications.” Nanoscale Advances, vol. 3, no. 5, Jan. 2021, pp. 1261-1292. https://xlink.rsc.org/?DOI=D0NA00873G.