Open Access
Prescribed drugs containing nitrogen heterocycles: an overview
2
DEPARTMENT OF CHEMISTRY
3
School of Science
5
Tehran
|
6
Iran
|
Publication type: Journal Article
Publication date: 2020-12-15
scimago Q1
wos Q2
SJR: 0.777
CiteScore: 7.6
Impact factor: 4.6
ISSN: 20462069
PubMed ID:
35557843
General Chemistry
General Chemical Engineering
Abstract
Heteroatoms as well as heterocyclic scaffolds are frequently present as the common cores in a plethora of active pharmaceuticals natural products. Statistically, more than 85% of all biologically active compounds are heterocycles or comprise a heterocycle and most frequently, nitrogen heterocycles as a backbone in their complex structures. These facts disclose and emphasize the vital role of heterocycles in modern drug design and drug discovery. In this review, we try to present a comprehensive overview of top prescribed drugs containing nitrogen heterocycles, describing their pharmacological properties, medical applications and their selected synthetic pathways. It is worth mentioning that the reported examples are actually limited to current top selling drugs, being or containing N-heterocycles and their synthetic information has been extracted from both scientific journals and the wider patent literature.
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Total citations:
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Citations from 2024:
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GOST
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M. Heravi M. et al. Prescribed drugs containing nitrogen heterocycles: an overview // RSC Advances. 2020. Vol. 10. No. 72. pp. 44247-44311.
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M. Heravi M., Zadsirjan V. Prescribed drugs containing nitrogen heterocycles: an overview // RSC Advances. 2020. Vol. 10. No. 72. pp. 44247-44311.
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RIS
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TY - JOUR
DO - 10.1039/D0RA09198G
UR - https://xlink.rsc.org/?DOI=D0RA09198G
TI - Prescribed drugs containing nitrogen heterocycles: an overview
T2 - RSC Advances
AU - M. Heravi, Majid
AU - Zadsirjan, Vahideh
PY - 2020
DA - 2020/12/15
PB - Royal Society of Chemistry (RSC)
SP - 44247-44311
IS - 72
VL - 10
PMID - 35557843
SN - 2046-2069
ER -
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BibTex (up to 50 authors)
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@article{2020_M. Heravi,
author = {Majid M. Heravi and Vahideh Zadsirjan},
title = {Prescribed drugs containing nitrogen heterocycles: an overview},
journal = {RSC Advances},
year = {2020},
volume = {10},
publisher = {Royal Society of Chemistry (RSC)},
month = {dec},
url = {https://xlink.rsc.org/?DOI=D0RA09198G},
number = {72},
pages = {44247--44311},
doi = {10.1039/D0RA09198G}
}
Cite this
MLA
Copy
M. Heravi, Majid, et al. “Prescribed drugs containing nitrogen heterocycles: an overview.” RSC Advances, vol. 10, no. 72, Dec. 2020, pp. 44247-44311. https://xlink.rsc.org/?DOI=D0RA09198G.