Organic and Biomolecular Chemistry, volume 19, issue 18, pages 3960-3982
Construction of bridged polycycles through dearomatization strategies
Publication type: Journal Article
Publication date: 2021-03-03
Journal:
Organic and Biomolecular Chemistry
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor: 3.2
ISSN: 14770520, 14770539
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
Bridged polycycles are privileged molecular skeletons with wide occurrence in bioactive natural products and pharmaceuticals. Therefore, they have been the pursing target molecules of numerous chemists. The rapid and convenient generation of sp3-rich complex three-dimensional molecular skeletons from simple and easily available aromatics has made dearomatization a highly valuable synthetic tool for the construction of rigid and challenging bridged rings. This review summarizes the-state-of-the-art advances of dearomatization strategies in the application of bridged ring formation, discusses their advantages and limitations and the in-depth mechanism, and highlights their synthetic value in the total synthesis of natural products. We wish this review will provide an important reference for medicinal and synthetic chemists and will inspire further development in this intriguing research area.
Top-30
Citations by journals
|
1
2
3
4
5
6
7
|
|
|
Organic Letters
7 publications, 14.89%
|
|
|
Chemical Communications
5 publications, 10.64%
|
|
|
Organic Chemistry Frontiers
5 publications, 10.64%
|
|
|
Advanced Synthesis and Catalysis
4 publications, 8.51%
|
|
|
Angewandte Chemie - International Edition
3 publications, 6.38%
|
|
|
Angewandte Chemie
3 publications, 6.38%
|
|
|
Organic and Biomolecular Chemistry
3 publications, 6.38%
|
|
|
Journal of Organic Chemistry
2 publications, 4.26%
|
|
|
Chemical Science
2 publications, 4.26%
|
|
|
Acta Chimica Sinica
1 publication, 2.13%
|
|
|
Journal of Flow Chemistry
1 publication, 2.13%
|
|
|
Chemical Record
1 publication, 2.13%
|
|
|
Chemistry - A European Journal
1 publication, 2.13%
|
|
|
Advances in Heterocyclic Chemistry
1 publication, 2.13%
|
|
|
European Journal of Organic Chemistry
1 publication, 2.13%
|
|
|
Chemical Papers
1 publication, 2.13%
|
|
|
Nature Synthesis
1 publication, 2.13%
|
|
|
Chemical Reviews
1 publication, 2.13%
|
|
|
Russian Chemical Reviews
1 publication, 2.13%
|
|
|
New Journal of Chemistry
1 publication, 2.13%
|
|
|
Journal of the American Chemical Society
1 publication, 2.13%
|
|
|
Medicinal Chemistry Research
1 publication, 2.13%
|
|
|
1
2
3
4
5
6
7
|
Citations by publishers
|
2
4
6
8
10
12
14
16
|
|
|
Royal Society of Chemistry (RSC)
16 publications, 34.04%
|
|
|
Wiley
13 publications, 27.66%
|
|
|
American Chemical Society (ACS)
11 publications, 23.4%
|
|
|
Springer Nature
3 publications, 6.38%
|
|
|
Shanghai Institute of Organic Chemistry
1 publication, 2.13%
|
|
|
Akademiai Kiado
1 publication, 2.13%
|
|
|
Elsevier
1 publication, 2.13%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 2.13%
|
|
|
2
4
6
8
10
12
14
16
|
- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2021,2022,2023,2024],"ids":[0,0,0,0],"codes":[0,0,0,0],"imageUrls":["","","",""],"datasets":[{"label":"Citations number","data":[8,11,13,15],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["17.02","23.4","27.66","31.91"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Organic Letters","Chemical Communications","Organic Chemistry Frontiers","Advanced Synthesis and Catalysis","Angewandte Chemie - International Edition","Angewandte Chemie","Organic and Biomolecular Chemistry","Journal of Organic Chemistry","Chemical Science","Acta Chimica Sinica","Journal of Flow Chemistry","Chemical Record","Chemistry - A European Journal","Advances in Heterocyclic Chemistry","European Journal of Organic Chemistry","Chemical Papers","Nature Synthesis","Chemical Reviews","Russian Chemical Reviews","New Journal of Chemistry","Journal of the American Chemical Society","Medicinal Chemistry Research"],"ids":[3315,9073,3991,3906,19215,25450,541,8697,9646,20619,5228,22413,24708,7227,19472,4048,29156,13718,23802,1404,4813,6106],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/6EJSsoiR4fNMNMPFBpMh5yKuYKcPXJDQKvKVeEMy_medium.webp","\/storage\/images\/resized\/lZ7ODGrM6PfzyKRLOh0nsqTcgHBMMYr9TkD5skBH_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/9Mus3KG1Tkd7Bwaurt8H3RwWh0CxRlGoO6ng9UK1_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp"],"datasets":[{"label":"","data":[7,5,5,4,3,3,3,2,2,1,1,1,1,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[14.89,10.64,10.64,8.51,6.38,6.38,6.38,4.26,4.26,2.13,2.13,2.13,2.13,2.13,2.13,2.13,2.13,2.13,2.13,2.13,2.13,2.13],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Royal Society of Chemistry (RSC)","Wiley","American Chemical Society (ACS)","Springer Nature","Shanghai Institute of Organic Chemistry","Akademiai Kiado","Elsevier","Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii"],"ids":[123,11,40,8,8960,7012,17,9422],"codes":[0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/6EJSsoiR4fNMNMPFBpMh5yKuYKcPXJDQKvKVeEMy_medium.webp","\/storage\/images\/resized\/lZ7ODGrM6PfzyKRLOh0nsqTcgHBMMYr9TkD5skBH_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/9Mus3KG1Tkd7Bwaurt8H3RwWh0CxRlGoO6ng9UK1_medium.webp"],"datasets":[{"label":"","data":[16,13,11,3,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[34.04,27.66,23.4,6.38,2.13,2.13,2.13,2.13],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"yearsCitationsQuartiles":{"type":"bar","data":{"show":true,"labels":[2021,2022,2023,2024],"ids":[],"codes":[],"imageUrls":[],"datasets":[{"label":"Q4","backgroundColor":"rgb(221,90,78)","data":[0,0,0,0],"percentage":["0","0","0","0"]},{"label":"Q3","backgroundColor":"rgb(251, 163,83)","data":[0,0,0,0],"percentage":["0","0","0","0"]},{"label":"Q2","backgroundColor":"rgb(232, 213, 89)","data":[1,0,3,2],"percentage":["2.13","0","6.38","4.26"]},{"label":"Q1","backgroundColor":"rgb(164, 207, 99)","data":[7,11,8,13],"percentage":["14.89","23.4","17.02","27.66"]},{"label":"Quartile not defined","backgroundColor":"#E5E7EB","data":[0,0,2,0],"percentage":["0","0","4.26","0"]}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations quartiles by SCImago per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"yearsCitationsQuartilesWs":{"type":"bar","data":{"show":true,"labels":[2021,2022,2023,2024],"ids":[],"codes":[],"imageUrls":[],"datasets":[{"label":"Q4","backgroundColor":"rgb(221,90,78)","data":[0,0,0,0],"percentage":["0","0","0","0"]},{"label":"Q3","backgroundColor":"rgb(251, 163,83)","data":[1,0,2,1],"percentage":["2.13","0","4.26","2.13"]},{"label":"Q2","backgroundColor":"rgb(232, 213, 89)","data":[1,3,4,3],"percentage":["2.13","6.38","8.51","6.38"]},{"label":"Q1","backgroundColor":"rgb(164, 207, 99)","data":[6,7,5,9],"percentage":["12.77","14.89","10.64","19.15"]},{"label":"Quartile not defined","backgroundColor":"#E5E7EB","data":[0,1,2,2],"percentage":["0","2.13","4.26","4.26"]}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations quartiles by WoS per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Zhang Z. et al. Construction of bridged polycycles through dearomatization strategies // Organic and Biomolecular Chemistry. 2021. Vol. 19. No. 18. pp. 3960-3982.
GOST all authors (up to 50)
Copy
Zhang Z., Han H., Wang L., Bu Z., Xie Y., Wang Q. Construction of bridged polycycles through dearomatization strategies // Organic and Biomolecular Chemistry. 2021. Vol. 19. No. 18. pp. 3960-3982.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1039/d1ob00096a
UR - https://doi.org/10.1039/d1ob00096a
TI - Construction of bridged polycycles through dearomatization strategies
T2 - Organic and Biomolecular Chemistry
AU - Zhang, Ziying
AU - Han, Huabin
AU - Bu, Zhanwei
AU - Wang, Qilin
AU - Wang, Lele
AU - Xie, Yan
PY - 2021
DA - 2021/03/03 00:00:00
PB - Royal Society of Chemistry (RSC)
SP - 3960-3982
IS - 18
VL - 19
SN - 1477-0520
SN - 1477-0539
ER -
Cite this
BibTex
Copy
@article{2021_Zhang,
author = {Ziying Zhang and Huabin Han and Zhanwei Bu and Qilin Wang and Lele Wang and Yan Xie},
title = {Construction of bridged polycycles through dearomatization strategies},
journal = {Organic and Biomolecular Chemistry},
year = {2021},
volume = {19},
publisher = {Royal Society of Chemistry (RSC)},
month = {mar},
url = {https://doi.org/10.1039/d1ob00096a},
number = {18},
pages = {3960--3982},
doi = {10.1039/d1ob00096a}
}
Cite this
MLA
Copy
Zhang, Ziying, et al. “Construction of bridged polycycles through dearomatization strategies.” Organic and Biomolecular Chemistry, vol. 19, no. 18, Mar. 2021, pp. 3960-3982. https://doi.org/10.1039/d1ob00096a.