Organic and Biomolecular Chemistry, volume 19, issue 18, pages 3960-3982
Construction of bridged polycycles through dearomatization strategies
Publication type: Journal Article
Publication date: 2021-03-03
Journal:
Organic and Biomolecular Chemistry
Q2
Q1
SJR: 0.607
CiteScore: 5.5
Impact factor: 2.9
ISSN: 14770520, 14770539
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
Bridged polycycles are privileged molecular skeletons with wide occurrence in bioactive natural products and pharmaceuticals. Therefore, they have been the pursing target molecules of numerous chemists. The rapid and convenient generation of sp3-rich complex three-dimensional molecular skeletons from simple and easily available aromatics has made dearomatization a highly valuable synthetic tool for the construction of rigid and challenging bridged rings. This review summarizes the-state-of-the-art advances of dearomatization strategies in the application of bridged ring formation, discusses their advantages and limitations and the in-depth mechanism, and highlights their synthetic value in the total synthesis of natural products. We wish this review will provide an important reference for medicinal and synthetic chemists and will inspire further development in this intriguing research area.
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Cite this
GOST
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Zhang Z. et al. Construction of bridged polycycles through dearomatization strategies // Organic and Biomolecular Chemistry. 2021. Vol. 19. No. 18. pp. 3960-3982.
GOST all authors (up to 50)
Copy
Zhang Z., Han H., Wang L., Bu Z., Xie Y., Wang Q. Construction of bridged polycycles through dearomatization strategies // Organic and Biomolecular Chemistry. 2021. Vol. 19. No. 18. pp. 3960-3982.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1039/d1ob00096a
UR - https://doi.org/10.1039/d1ob00096a
TI - Construction of bridged polycycles through dearomatization strategies
T2 - Organic and Biomolecular Chemistry
AU - Zhang, Ziying
AU - Han, Huabin
AU - Wang, Lele
AU - Bu, Zhanwei
AU - Xie, Yan
AU - Wang, Qilin
PY - 2021
DA - 2021/03/03
PB - Royal Society of Chemistry (RSC)
SP - 3960-3982
IS - 18
VL - 19
SN - 1477-0520
SN - 1477-0539
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Zhang,
author = {Ziying Zhang and Huabin Han and Lele Wang and Zhanwei Bu and Yan Xie and Qilin Wang},
title = {Construction of bridged polycycles through dearomatization strategies},
journal = {Organic and Biomolecular Chemistry},
year = {2021},
volume = {19},
publisher = {Royal Society of Chemistry (RSC)},
month = {mar},
url = {https://doi.org/10.1039/d1ob00096a},
number = {18},
pages = {3960--3982},
doi = {10.1039/d1ob00096a}
}
Cite this
MLA
Copy
Zhang, Ziying, et al. “Construction of bridged polycycles through dearomatization strategies.” Organic and Biomolecular Chemistry, vol. 19, no. 18, Mar. 2021, pp. 3960-3982. https://doi.org/10.1039/d1ob00096a.