Molecular hydrogels of therapeutic agents
Тип публикации: Journal Article
Дата публикации: 2009-02-13
scimago Q1
wos Q1
БС1
SJR: 11.467
CiteScore: 73.2
Impact factor: 39
ISSN: 03060012, 14604744
PubMed ID:
19421568
General Chemistry
Краткое описание
This tutorial review aims to introduce a new kind of biomaterials-molecular hydrogels of therapeutic agents. Based on the molecular self-assembly in water, it is possible to transform therapeutic agents into analogues that form hydrogels without compromising their pharmacological efficacy. This transformation can be beneficial in three aspects: (i) the therapeutic agents become "self-deliverable" in the form of hydrogels; (ii) the self-assembly of hydrogelators of drugs might confer new and useful properties such as multivalency or high local densities; (iii) the exploration of molecular hydrogels of drugs may ultimately lead to bioactive molecules that have dual or multiple roles. By summarizing the reports on the molecular hydrogels made from clinical used drugs or other bioactive molecules, this article presents representative molecular hydrogels of therapeutics and outlines the promises and challenges for developing this new class of biomaterials.
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ГОСТ
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Zhao F. et al. Molecular hydrogels of therapeutic agents // Chemical Society Reviews. 2009. Vol. 38. No. 4. p. 883.
ГОСТ со всеми авторами (до 50)
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Zhao F., Ma M. L., Xu B. Molecular hydrogels of therapeutic agents // Chemical Society Reviews. 2009. Vol. 38. No. 4. p. 883.
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RIS
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TY - JOUR
DO - 10.1039/b806410p
UR - https://doi.org/10.1039/b806410p
TI - Molecular hydrogels of therapeutic agents
T2 - Chemical Society Reviews
AU - Zhao, Fan
AU - Ma, Man Lung
AU - Xu, Bing
PY - 2009
DA - 2009/02/13
PB - Royal Society of Chemistry (RSC)
SP - 883
IS - 4
VL - 38
PMID - 19421568
SN - 0306-0012
SN - 1460-4744
ER -
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@article{2009_Zhao,
author = {Fan Zhao and Man Lung Ma and Bing Xu},
title = {Molecular hydrogels of therapeutic agents},
journal = {Chemical Society Reviews},
year = {2009},
volume = {38},
publisher = {Royal Society of Chemistry (RSC)},
month = {feb},
url = {https://doi.org/10.1039/b806410p},
number = {4},
pages = {883},
doi = {10.1039/b806410p}
}
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MLA
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Zhao, Fan, et al. “Molecular hydrogels of therapeutic agents.” Chemical Society Reviews, vol. 38, no. 4, Feb. 2009, p. 883. https://doi.org/10.1039/b806410p.