Open Access
Open access
volume 9 issue 15 pages 3866-3880

Molecular mechanism of lytic polysaccharide monooxygenases

Erik D. Hedegard 1, 2, 3, 4
Ulf Ryde 1, 2, 3, 4
1
 
Department of Theoretical Chemistry
3
 
Lund
4
 
SWEDEN
Publication typeJournal Article
Publication date2018-03-26
scimago Q1
wos Q1
SJR2.138
CiteScore12.6
Impact factor7.4
ISSN20416520, 20416539
PubMed ID:  29780519
General Chemistry
Abstract

The lytic polysaccharide monooxygenases (LPMOs) are copper metalloenzymes that can enhance polysaccharide depolymerization through an oxidative mechanism and hence boost generation of biofuel from e.g. cellulose. By employing density functional theory in a combination of quantum mechanics and molecular mechanics (QM/MM), we report a complete description of the molecular mechanism of LPMOs.

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GOST |
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GOST Copy
D. Hedegard E. et al. Molecular mechanism of lytic polysaccharide monooxygenases // Chemical Science. 2018. Vol. 9. No. 15. pp. 3866-3880.
GOST all authors (up to 50) Copy
D. Hedegard E., Ryde U. Molecular mechanism of lytic polysaccharide monooxygenases // Chemical Science. 2018. Vol. 9. No. 15. pp. 3866-3880.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1039/c8sc00426a
UR - https://doi.org/10.1039/c8sc00426a
TI - Molecular mechanism of lytic polysaccharide monooxygenases
T2 - Chemical Science
AU - D. Hedegard, Erik
AU - Ryde, Ulf
PY - 2018
DA - 2018/03/26
PB - Royal Society of Chemistry (RSC)
SP - 3866-3880
IS - 15
VL - 9
PMID - 29780519
SN - 2041-6520
SN - 2041-6539
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2018_D. Hedegard,
author = {Erik D. Hedegard and Ulf Ryde},
title = {Molecular mechanism of lytic polysaccharide monooxygenases},
journal = {Chemical Science},
year = {2018},
volume = {9},
publisher = {Royal Society of Chemistry (RSC)},
month = {mar},
url = {https://doi.org/10.1039/c8sc00426a},
number = {15},
pages = {3866--3880},
doi = {10.1039/c8sc00426a}
}
MLA
Cite this
MLA Copy
D. Hedegard, Erik, et al. “Molecular mechanism of lytic polysaccharide monooxygenases.” Chemical Science, vol. 9, no. 15, Mar. 2018, pp. 3866-3880. https://doi.org/10.1039/c8sc00426a.