volume 55 issue 50 pages 7235-7238

Parahydrogen induced hyperpolarization provides a tool for NMR metabolomics at nanomolar concentrations

Lisanne Sellies 1, 2, 3, 4
Indrek Reile 5, 6, 7, 8
Ruud L. E. G. Aspers 1
Martin Feiters 1, 2, 3, 4
Floris P. J. T. Rutjes 1, 2, 3, 4
M. Tessari 1, 2, 3, 4
Publication typeJournal Article
Publication date2019-05-30
scimago Q1
wos Q2
SJR1.037
CiteScore7.4
Impact factor4.2
ISSN13597345, 1364548X
PubMed ID:  31165813
Materials Chemistry
Metals and Alloys
Surfaces, Coatings and Films
General Chemistry
Ceramics and Composites
Electronic, Optical and Magnetic Materials
Catalysis
Abstract
An NMR approach based on parahydrogen hyperpolarization is presented to detect and resolve specific classes of metabolites in complex biomixtures at down to nanomolar concentrations. We demonstrate our method on solid phase extracts of urine, by simultaneously observing hundreds of metabolites well below the limits of detection of thermal NMR.
Found 
Found 

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GOST Copy
Sellies L. et al. Parahydrogen induced hyperpolarization provides a tool for NMR metabolomics at nanomolar concentrations // Chemical Communications. 2019. Vol. 55. No. 50. pp. 7235-7238.
GOST all authors (up to 50) Copy
Sellies L., Reile I., Aspers R. L. E. G., Feiters M., Rutjes F. P. J. T., Tessari M. Parahydrogen induced hyperpolarization provides a tool for NMR metabolomics at nanomolar concentrations // Chemical Communications. 2019. Vol. 55. No. 50. pp. 7235-7238.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1039/c9cc02186h
UR - https://xlink.rsc.org/?DOI=C9CC02186H
TI - Parahydrogen induced hyperpolarization provides a tool for NMR metabolomics at nanomolar concentrations
T2 - Chemical Communications
AU - Sellies, Lisanne
AU - Reile, Indrek
AU - Aspers, Ruud L. E. G.
AU - Feiters, Martin
AU - Rutjes, Floris P. J. T.
AU - Tessari, M.
PY - 2019
DA - 2019/05/30
PB - Royal Society of Chemistry (RSC)
SP - 7235-7238
IS - 50
VL - 55
PMID - 31165813
SN - 1359-7345
SN - 1364-548X
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2019_Sellies,
author = {Lisanne Sellies and Indrek Reile and Ruud L. E. G. Aspers and Martin Feiters and Floris P. J. T. Rutjes and M. Tessari},
title = {Parahydrogen induced hyperpolarization provides a tool for NMR metabolomics at nanomolar concentrations},
journal = {Chemical Communications},
year = {2019},
volume = {55},
publisher = {Royal Society of Chemistry (RSC)},
month = {may},
url = {https://xlink.rsc.org/?DOI=C9CC02186H},
number = {50},
pages = {7235--7238},
doi = {10.1039/c9cc02186h}
}
MLA
Cite this
MLA Copy
Sellies, Lisanne, et al. “Parahydrogen induced hyperpolarization provides a tool for NMR metabolomics at nanomolar concentrations.” Chemical Communications, vol. 55, no. 50, May. 2019, pp. 7235-7238. https://xlink.rsc.org/?DOI=C9CC02186H.