Modifications of amino acids using arenediazonium salts
2
Department of Organic Chemistry
4
Bangalore
5
INDIA
|
Publication type: Journal Article
Publication date: 2019-08-23
scimago Q2
wos Q2
SJR: 0.600
CiteScore: 5.2
Impact factor: 2.7
ISSN: 14770520, 14770539
PubMed ID:
31469151
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
Aryl transfer reactions from arenediazonium salts have started to make their impact in chemical biology with initial forays in the arena of arylative modifications and bio-conjugations of amino acids, peptides and proteins. The unique multimodal reactivity of arenediazonium salts, ranging from thermal or photochemical radical chain reactions, Pd-catalyzed coupling to arylazo-coupling reactions, all under distinct but mild conditions, provides multiple options for side chain modifications of amino acids and peptides and in addition, site-selective protein conjugation and labelling, protein immobilization, azo-bridged macrocyclization, etc. under bio-ambient conditions. The purpose of this review is to highlight these recent advances and to stimulate interest towards broader applications of arenediazonium salts as aryl transfer agents in bioconjugation reactions.
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Total citations:
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Citations from 2025:
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(10.2%)
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GOST
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Sengupta S. et al. Modifications of amino acids using arenediazonium salts // Organic and Biomolecular Chemistry. 2019. Vol. 17. No. 36. pp. 8308-8329.
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Sengupta S., Chandrasekaran S. Modifications of amino acids using arenediazonium salts // Organic and Biomolecular Chemistry. 2019. Vol. 17. No. 36. pp. 8308-8329.
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RIS
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TY - JOUR
DO - 10.1039/c9ob01471c
UR - https://xlink.rsc.org/?DOI=C9OB01471C
TI - Modifications of amino acids using arenediazonium salts
T2 - Organic and Biomolecular Chemistry
AU - Sengupta, Saumitra
AU - Chandrasekaran, S.
PY - 2019
DA - 2019/08/23
PB - Royal Society of Chemistry (RSC)
SP - 8308-8329
IS - 36
VL - 17
PMID - 31469151
SN - 1477-0520
SN - 1477-0539
ER -
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BibTex (up to 50 authors)
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@article{2019_Sengupta,
author = {Saumitra Sengupta and S. Chandrasekaran},
title = {Modifications of amino acids using arenediazonium salts},
journal = {Organic and Biomolecular Chemistry},
year = {2019},
volume = {17},
publisher = {Royal Society of Chemistry (RSC)},
month = {aug},
url = {https://xlink.rsc.org/?DOI=C9OB01471C},
number = {36},
pages = {8308--8329},
doi = {10.1039/c9ob01471c}
}
Cite this
MLA
Copy
Sengupta, Saumitra, et al. “Modifications of amino acids using arenediazonium salts.” Organic and Biomolecular Chemistry, vol. 17, no. 36, Aug. 2019, pp. 8308-8329. https://xlink.rsc.org/?DOI=C9OB01471C.