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Chemical Science, volume 12, issue 22, pages 7735-7745

Stalling chromophore synthesis of the fluorescent protein Venus reveals the molecular basis of the final oxidation step

Auhim Husam Sabah 1, 2
Grigorenko Bella 3, 4
Harris Tessa K 1
Aksakal Ozan E 1
Polyakov Igor V. 3, 4
Berry Colin 1
Jones D. Dafydd 1
1
 
School of Biosciences, Molecular Biosciences Division, Cardiff University, Sir Martin Evans Building, Cardiff, UK
5
 
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON M5S 3H6, Canada
6
 
Department of Computer Science, University of Toronto, 214 College St., Toronto, Ontario M5T 3A1, Canada
8
 
School of Medicine, Cardiff University, UK
Publication typeJournal Article
Publication date2021-03-31
Journal: Chemical Science
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor8.4
ISSN20416520, 20416539
PubMed ID:  34168826
General Chemistry
Abstract

Fluorescent proteins (FPs) have revolutionised the life sciences, but the chromophore maturation mechanism is still not fully understood. Here we photochemically trap maturation at a crucial stage and structurally characterise the intermediate.

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GOST Copy
Auhim H. S. et al. Stalling chromophore synthesis of the fluorescent protein Venus reveals the molecular basis of the final oxidation step // Chemical Science. 2021. Vol. 12. No. 22. pp. 7735-7745.
GOST all authors (up to 50) Copy
Auhim H. S., Grigorenko B., Harris T. K., Aksakal O. E., Polyakov I. V., Berry C., Gomes G. D. P., Alabugin I. V., Rizkallah P. J., Nemukhin A., Jones D. D. Stalling chromophore synthesis of the fluorescent protein Venus reveals the molecular basis of the final oxidation step // Chemical Science. 2021. Vol. 12. No. 22. pp. 7735-7745.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1039/d0sc06693a
UR - https://doi.org/10.1039%2Fd0sc06693a
TI - Stalling chromophore synthesis of the fluorescent protein Venus reveals the molecular basis of the final oxidation step
T2 - Chemical Science
AU - Harris, Tessa K
AU - Aksakal, Ozan E
AU - Berry, Colin
AU - Gomes, Gabriel Dos Passos
AU - Alabugin, Igor V.
AU - Rizkallah, Pierre J.
AU - Nemukhin, Alexander
AU - Jones, D. Dafydd
AU - Polyakov, Igor V.
AU - Auhim, Husam Sabah
AU - Grigorenko, Bella
PY - 2021
DA - 2021/03/31 00:00:00
PB - Royal Society of Chemistry (RSC)
SP - 7735-7745
IS - 22
VL - 12
PMID - 34168826
SN - 2041-6520
SN - 2041-6539
ER -
BibTex |
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BibTex Copy
@article{2021_Auhim,
author = {Tessa K Harris and Ozan E Aksakal and Colin Berry and Gabriel Dos Passos Gomes and Igor V. Alabugin and Pierre J. Rizkallah and Alexander Nemukhin and D. Dafydd Jones and Igor V. Polyakov and Husam Sabah Auhim and Bella Grigorenko},
title = {Stalling chromophore synthesis of the fluorescent protein Venus reveals the molecular basis of the final oxidation step},
journal = {Chemical Science},
year = {2021},
volume = {12},
publisher = {Royal Society of Chemistry (RSC)},
month = {mar},
url = {https://doi.org/10.1039%2Fd0sc06693a},
number = {22},
pages = {7735--7745},
doi = {10.1039/d0sc06693a}
}
MLA
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MLA Copy
Auhim, Husam Sabah, et al. “Stalling chromophore synthesis of the fluorescent protein Venus reveals the molecular basis of the final oxidation step.” Chemical Science, vol. 12, no. 22, Mar. 2021, pp. 7735-7745. https://doi.org/10.1039%2Fd0sc06693a.
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