Journal of Materials Chemistry B

, volume 8 , issue 41 , pages 9385-9403

Cationic dynamic covalent polymers for gene transfection

Dandan Su ^{1, 2, 3, 4, 5, 6, 7}

Maëva Coste ^{2, 6, 7, 8, 9, 10}

Andrei Diaconu ¹¹

Mihail Barboiu ^{1, 3, 4, 5, 6, 7}

Sébastien Ulrich ^{2, 6, 7, 8, 9, 10}

Hide authors affiliations Show authors affiliations: 11 affiliations

Institut Européen des Membranes, Adaptive Supramolecular Nanosystems Group, University of Montpellier, ENSCM, CNRS, Place Eugène Bataillon, CC 047, Montpellier, France

University of Montpellier

Institut Européen des Membranes

Institut des Biomolécules Max Mousseron (IBMM), CNRS, Université of Montpellier, ENSCM, Montpellier, France |

Institut Européen des Membranes |

⁴

Adaptive Supramolecular Nanosystems Group

⁵

UNIVERSITY OF MONTPELLIER |

⁶

ENSCM

⁷

CNRS

⁸

Institut des Biomolécules Max Mousseron (IBMM)

⁹

Université of Montpellier |

¹⁰

Montpellier |

¹¹

Petru Poni” Institute of Macromolecular Chemistry of Romanian Academy, 41A, Aleea Gr. Ghica Voda, Iasi, Romania |

Publication type: Journal Article

Publication date: 2020-09-11

Royal Society of Chemistry (RSC)

Journal of Materials Chemistry B

scimago Q1

wos Q2

SJR: 1.159

CiteScore: 10.4

Impact factor: 5.7

ISSN: 20507518, 2050750X

DOI: 10.1039/d0tb01836h

Copy DOI

PubMed ID: 33048107

General Chemistry

General Medicine

General Materials Science

Biomedical Engineering

Abstract

Dynamic covalent polymers are materials formed by reversible covalent bonds and non-covalent interactions through an adaptive constitutional dynamic chemistry. The implementation of dynamic covalent polymers in gene delivery has recently emerged due to their responsive and adaptive features. Indeed, such an approach offers the alluring promise of discovering optimal delivery vectors self-fitted to their nucleic acid cargos and responsive to environmental changes (e.g. pH changes or the presence of a biomolecular target). This review will discuss more precisely the structural features of the molecular building blocks used so far, the architecture of the resulting dynamic covalent polymers from linear to 2D and 3D, and the covalent and supramolecular self-assembly processes at play in nucleic acid recognition and delivery, showcasing in particular the very few examples of adaptive self-assembly of dynamic covalent polymers templated by nucleic acids and responsive to the presence of biomolecular targets found in cell membranes that facilitate cell entry.

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GOST |

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GOST Copy

Su D. et al. Cationic dynamic covalent polymers for gene transfection // Journal of Materials Chemistry B. 2020. Vol. 8. No. 41. pp. 9385-9403.

GOST all authors (up to 50) Copy

Su D., Coste M., Diaconu A., Barboiu M., Ulrich S. Cationic dynamic covalent polymers for gene transfection // Journal of Materials Chemistry B. 2020. Vol. 8. No. 41. pp. 9385-9403.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1039/d0tb01836h

UR - https://xlink.rsc.org/?DOI=D0TB01836H

TI - Cationic dynamic covalent polymers for gene transfection

T2 - Journal of Materials Chemistry B

AU - Su, Dandan

AU - Coste, Maëva

AU - Diaconu, Andrei

AU - Barboiu, Mihail

AU - Ulrich, Sébastien

PY - 2020

DA - 2020/09/11

PB - Royal Society of Chemistry (RSC)

SP - 9385-9403

IS - 41

VL - 8

PMID - 33048107

SN - 2050-7518

SN - 2050-750X

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2020_Su,

author = {Dandan Su and Maëva Coste and Andrei Diaconu and Mihail Barboiu and Sébastien Ulrich},

title = {Cationic dynamic covalent polymers for gene transfection},

journal = {Journal of Materials Chemistry B},

year = {2020},

volume = {8},

publisher = {Royal Society of Chemistry (RSC)},

month = {sep},

url = {https://xlink.rsc.org/?DOI=D0TB01836H},

number = {41},

pages = {9385--9403},

doi = {10.1039/d0tb01836h}

}

MLA

Cite this

MLA Copy

Su, Dandan, et al. “Cationic dynamic covalent polymers for gene transfection.” Journal of Materials Chemistry B, vol. 8, no. 41, Sep. 2020, pp. 9385-9403. https://xlink.rsc.org/?DOI=D0TB01836H.

Publisher

Royal Society of Chemistry (RSC)

Journal

Journal of Materials Chemistry B

scimago Q1

wos Q2

SJR

1.159

CiteScore

10.4

Impact factor

5.7

ISSN

20507518 (Print, Electronic)

2050750X (Print, Electronic)

Profiles

Mihail Dumitru Barboiu