Continuous flow mechanochemistry: reactive extrusion as an enabling technology in organic synthesis
Robert R A Bolt
1, 2
,
Jamie A. Leitch
1, 2
,
Andrew C Jones
3, 4
,
William I Nicholson
3, 4
,
Duncan L. Browne
1, 2
Publication type: Journal Article
Publication date: 2022-05-04
scimago Q1
wos Q1
SJR: 11.467
CiteScore: 73.2
Impact factor: 39.0
ISSN: 03060012, 14604744
PubMed ID:
35506866
General Chemistry
Abstract
Rapid and wide-ranging developments have established mechanochemistry as a powerful avenue in sustainable organic synthesis. This is primarily due to unique opportunities which have been offered in solvent-free - or highly solvent-minimised - reaction systems. Nevertheless, despite elegant advances in ball-milling technology, limitations in scale-up still remain. This tutorial review covers the first reports into the translation from "batch-mode" ball-milling to "flow-mode" reactive extrusion, using twin-screw extrusion.
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Metrics
150
Total citations:
150
Citations from 2024:
99
(67.34%)
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GOST
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Bolt R. R. A. et al. Continuous flow mechanochemistry: reactive extrusion as an enabling technology in organic synthesis // Chemical Society Reviews. 2022. Vol. 51. No. 11. pp. 4243-4260.
GOST all authors (up to 50)
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Bolt R. R. A., Leitch J. A., Jones A. C., Nicholson W. I., Browne D. L. Continuous flow mechanochemistry: reactive extrusion as an enabling technology in organic synthesis // Chemical Society Reviews. 2022. Vol. 51. No. 11. pp. 4243-4260.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1039/d1cs00657f
UR - https://xlink.rsc.org/?DOI=D1CS00657F
TI - Continuous flow mechanochemistry: reactive extrusion as an enabling technology in organic synthesis
T2 - Chemical Society Reviews
AU - Bolt, Robert R A
AU - Leitch, Jamie A.
AU - Jones, Andrew C
AU - Nicholson, William I
AU - Browne, Duncan L.
PY - 2022
DA - 2022/05/04
PB - Royal Society of Chemistry (RSC)
SP - 4243-4260
IS - 11
VL - 51
PMID - 35506866
SN - 0306-0012
SN - 1460-4744
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2022_Bolt,
author = {Robert R A Bolt and Jamie A. Leitch and Andrew C Jones and William I Nicholson and Duncan L. Browne},
title = {Continuous flow mechanochemistry: reactive extrusion as an enabling technology in organic synthesis},
journal = {Chemical Society Reviews},
year = {2022},
volume = {51},
publisher = {Royal Society of Chemistry (RSC)},
month = {may},
url = {https://xlink.rsc.org/?DOI=D1CS00657F},
number = {11},
pages = {4243--4260},
doi = {10.1039/d1cs00657f}
}
Cite this
MLA
Copy
Bolt, Robert R. A., et al. “Continuous flow mechanochemistry: reactive extrusion as an enabling technology in organic synthesis.” Chemical Society Reviews, vol. 51, no. 11, May. 2022, pp. 4243-4260. https://xlink.rsc.org/?DOI=D1CS00657F.