Antitumor activity of tridentate pincer and related metal complexes
Shulei Wu
1, 2, 3, 4, 5, 6
,
Zaoduan Wu
1, 2, 3, 4, 5, 6
,
Qianyi Ge
1, 2, 3, 4, 5, 6
,
Xing Zheng
1
,
Zehua Yang
1, 2, 3, 4, 5, 6
2
Hunan Provincial Key Laboratory of tumor microenvironment responsive drug research
|
3
Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study
|
4
Institute of Pharmacy & Pharmacology
5
Affiliated Nanhua Hospital
Publication type: Journal Article
Publication date: 2021-05-06
scimago Q2
wos Q2
SJR: 0.600
CiteScore: 5.2
Impact factor: 2.7
ISSN: 14770520, 14770539
PubMed ID:
34059868
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
Pincer complexes featuring tunable tridentate ligand frameworks are one of the most actively studied classes of metal-based complexes. Currently, growing attention is devoted to the cytotoxicity of pincer and related metal complexes. The antiproliferative activity of numerous pincer complexes has been reported. Pincer tridentate ligand scaffolds show different coordination modes and offer multiple options for directed structural modifications. This review summarizes the significant progress in the research studies of the antitumor activity of pincer and related platinum(ii), gold(iii), palladium(ii), copper(ii), iron(iii), ruthenium(ii), nickel(ii) and some other metal complexes, in order to provide a reference for designing novel metal coordination drug candidates with promising antitumor activity.
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Metrics
34
Total citations:
34
Citations from 2025:
13
(38.24%)
Cite this
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RIS |
BibTex |
MLA
Cite this
GOST
Copy
Wu S. et al. Antitumor activity of tridentate pincer and related metal complexes // Organic and Biomolecular Chemistry. 2021. Vol. 19. No. 24. pp. 5254-5273.
GOST all authors (up to 50)
Copy
Wu S., Wu Z., Ge Q., Zheng X., Yang Z. Antitumor activity of tridentate pincer and related metal complexes // Organic and Biomolecular Chemistry. 2021. Vol. 19. No. 24. pp. 5254-5273.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1039/d1ob00577d
UR - https://xlink.rsc.org/?DOI=D1OB00577D
TI - Antitumor activity of tridentate pincer and related metal complexes
T2 - Organic and Biomolecular Chemistry
AU - Wu, Shulei
AU - Wu, Zaoduan
AU - Ge, Qianyi
AU - Zheng, Xing
AU - Yang, Zehua
PY - 2021
DA - 2021/05/06
PB - Royal Society of Chemistry (RSC)
SP - 5254-5273
IS - 24
VL - 19
PMID - 34059868
SN - 1477-0520
SN - 1477-0539
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Wu,
author = {Shulei Wu and Zaoduan Wu and Qianyi Ge and Xing Zheng and Zehua Yang},
title = {Antitumor activity of tridentate pincer and related metal complexes},
journal = {Organic and Biomolecular Chemistry},
year = {2021},
volume = {19},
publisher = {Royal Society of Chemistry (RSC)},
month = {may},
url = {https://xlink.rsc.org/?DOI=D1OB00577D},
number = {24},
pages = {5254--5273},
doi = {10.1039/d1ob00577d}
}
Cite this
MLA
Copy
Wu, Shulei, et al. “Antitumor activity of tridentate pincer and related metal complexes.” Organic and Biomolecular Chemistry, vol. 19, no. 24, May. 2021, pp. 5254-5273. https://xlink.rsc.org/?DOI=D1OB00577D.