4′-Fluoro-nucleosides and nucleotides: from nucleocidin to an emerging class of therapeutics
Publication type: Journal Article
Publication date: 2023-01-01
scimago Q1
wos Q1
SJR: 11.467
CiteScore: 73.2
Impact factor: 39.0
ISSN: 03060012, 14604744
PubMed ID:
36472161
General Chemistry
Abstract
The history and development of 4′-fluoro-nucleosides is discussed in this review. This is a class of nucleosides which have their origin in the discovery of the rare fluorine containing natural product nucleocidin. Nucleocidin contains a fluorine atom located at the 4′-position of its ribose ring. From its early isolation as an unexpected natural product, to its total synthesis and bioactivity assessment, nucleocidin has played a role in inspiring the exploration of 4′-fluoro-nucleosides as a privileged motif for nucleoside-based therapeutics.
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19
Total citations:
19
Citations from 2024:
13
(68%)
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MLA
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GOST
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LOWE P. J., O'Hagan D. 4′-Fluoro-nucleosides and nucleotides: from nucleocidin to an emerging class of therapeutics // Chemical Society Reviews. 2023. Vol. 52. No. 1. pp. 248-276.
GOST all authors (up to 50)
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LOWE P. J., O'Hagan D. 4′-Fluoro-nucleosides and nucleotides: from nucleocidin to an emerging class of therapeutics // Chemical Society Reviews. 2023. Vol. 52. No. 1. pp. 248-276.
Cite this
RIS
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TY - JOUR
DO - 10.1039/d2cs00762b
UR - https://xlink.rsc.org/?DOI=D2CS00762B
TI - 4′-Fluoro-nucleosides and nucleotides: from nucleocidin to an emerging class of therapeutics
T2 - Chemical Society Reviews
AU - LOWE, PHILLIP J.
AU - O'Hagan, David
PY - 2023
DA - 2023/01/01
PB - Royal Society of Chemistry (RSC)
SP - 248-276
IS - 1
VL - 52
PMID - 36472161
SN - 0306-0012
SN - 1460-4744
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2023_LOWE,
author = {PHILLIP J. LOWE and David O'Hagan},
title = {4′-Fluoro-nucleosides and nucleotides: from nucleocidin to an emerging class of therapeutics},
journal = {Chemical Society Reviews},
year = {2023},
volume = {52},
publisher = {Royal Society of Chemistry (RSC)},
month = {jan},
url = {https://xlink.rsc.org/?DOI=D2CS00762B},
number = {1},
pages = {248--276},
doi = {10.1039/d2cs00762b}
}
Cite this
MLA
Copy
LOWE, PHILLIP J., and David O'Hagan. “4′-Fluoro-nucleosides and nucleotides: from nucleocidin to an emerging class of therapeutics.” Chemical Society Reviews, vol. 52, no. 1, Jan. 2023, pp. 248-276. https://xlink.rsc.org/?DOI=D2CS00762B.