Open Access
Open access
Springer Nature
Bioscience Reports
,  volume 40 ,  issue 1

Interplay of mRNA capping and transcription machineries

Publication type: Journal Article
Publication date: 2020-01-06
Springer Nature
scimago Q1
wos Q1
SJR: 0.899
CiteScore: 8.0
Impact factor: 4.7
ISSN: 01448463, 15734935
DOI:  10.1042/BSR20192825
PubMed ID:  31904821
Biochemistry
Molecular Biology
Cell Biology
Biophysics
Abstract

Early stages of transcription from eukaryotic promoters include two principal events: the capping of newly synthesized mRNA and the transition of RNA polymerase II from the preinitiation complex to the productive elongation state. The capping checkpoint model implies that these events are tightly coupled, which is necessary for ensuring the proper capping of newly synthesized mRNA. Recent findings also show that the capping machinery has a wider effect on transcription and the entire gene expression process. The molecular basis of these phenomena is discussed.

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GOST Copy
Kachaev Z. M. et al. Interplay of mRNA capping and transcription machineries // Bioscience Reports. 2020. Vol. 40. No. 1.
GOST all authors (up to 50) Copy
Kachaev Z. M., Lebedeva L. A., Kozlov E. N., Shidlovskii Y. V. Interplay of mRNA capping and transcription machineries // Bioscience Reports. 2020. Vol. 40. No. 1.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1042/BSR20192825
UR - https://doi.org/10.1042/BSR20192825
TI - Interplay of mRNA capping and transcription machineries
T2 - Bioscience Reports
AU - Kachaev, Zaur M.
AU - Lebedeva, Lyubov A.
AU - Kozlov, Eugene N.
AU - Shidlovskii, Y. V.
PY - 2020
DA - 2020/01/06
PB - Springer Nature
IS - 1
VL - 40
PMID - 31904821
SN - 0144-8463
SN - 1573-4935
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2020_Kachaev,
author = {Zaur M. Kachaev and Lyubov A. Lebedeva and Eugene N. Kozlov and Y. V. Shidlovskii},
title = {Interplay of mRNA capping and transcription machineries},
journal = {Bioscience Reports},
year = {2020},
volume = {40},
publisher = {Springer Nature},
month = {jan},
url = {https://doi.org/10.1042/BSR20192825},
number = {1},
doi = {10.1042/BSR20192825}
}