Antimicrobial, Cytotoxic Lignans and Terpenoids from the Twigs ofPseudolarix kaempferi
Publication type: Journal Article
Publication date: 2011-07-04
scimago Q2
wos Q2
SJR: 0.427
CiteScore: 4.5
Impact factor: 2.0
ISSN: 00320943, 14390221
PubMed ID:
21728150
Organic Chemistry
Drug Discovery
Pharmacology
Pharmaceutical Science
Molecular Medicine
Complementary and alternative medicine
Analytical Chemistry
Abstract
Seven new compounds, including four lignans, (+)-(8S,8′S)-9,9′-dibenzoylsecoisolariciresinol (1), (+)-(8S*,8′R*)-4,4′-dimethyloxomatairesinol (2), (+)-(7S*,8R*,8′R*,9′S*)-9′-n-butoxytsugacetal (3), and pseudolarkaemin A (4), a pyronane glycoside, pseudolarkaemin B (5), an ent-beyerene glycoside, pseudolarkaemin C (6), and a triterpene, 25-epi-pseudolarolide Q (7), along with 25 known compounds (8–32) were isolated from the twigs of Pseudolarix kaempferi. Their structures were elucidated mainly by the analysis of their NMR and MS data. Pseudolarolide C acid (24) was isolated for the first time as a natural product. All compounds were evaluated for antimicrobial activity against Candida albicans and Staphylococcus aureus, and cytotoxic activity against K562, HT-29, B16, BGC-823, BEL-7402, SGC-7901, U251, and A549 cancer cell lines were assayed. Results indicated that the new compounds 3, 7, and some known compounds showed antimicrobial and cytotoxic activities.
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Total citations:
34
Citations from 2024:
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(14.7%)
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MLA
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GOST
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He W. Antimicrobial, Cytotoxic Lignans and Terpenoids from the Twigs ofPseudolarix kaempferi // Planta Medica. 2011. Vol. 77. No. 17. pp. 1924-1931.
GOST all authors (up to 50)
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He W. Antimicrobial, Cytotoxic Lignans and Terpenoids from the Twigs ofPseudolarix kaempferi // Planta Medica. 2011. Vol. 77. No. 17. pp. 1924-1931.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1055/s-0031-1280020
UR - https://doi.org/10.1055/s-0031-1280020
TI - Antimicrobial, Cytotoxic Lignans and Terpenoids from the Twigs ofPseudolarix kaempferi
T2 - Planta Medica
AU - He, Wen-Jun
PY - 2011
DA - 2011/07/04
PB - Georg Thieme Verlag KG
SP - 1924-1931
IS - 17
VL - 77
PMID - 21728150
SN - 0032-0943
SN - 1439-0221
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2011_He,
author = {Wen-Jun He},
title = {Antimicrobial, Cytotoxic Lignans and Terpenoids from the Twigs ofPseudolarix kaempferi},
journal = {Planta Medica},
year = {2011},
volume = {77},
publisher = {Georg Thieme Verlag KG},
month = {jul},
url = {https://doi.org/10.1055/s-0031-1280020},
number = {17},
pages = {1924--1931},
doi = {10.1055/s-0031-1280020}
}
Cite this
MLA
Copy
He, Wen-Jun. “Antimicrobial, Cytotoxic Lignans and Terpenoids from the Twigs ofPseudolarix kaempferi.” Planta Medica, vol. 77, no. 17, Jul. 2011, pp. 1924-1931. https://doi.org/10.1055/s-0031-1280020.
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