Synthesis, volume 2002, issue 06, pages 753-756
Synthesis of New Ethyl 3-Amino-4-arylfuran-2-carboxylates
Publication type: Journal Article
Publication date: 2002-07-26
Catalysis
Organic Chemistry
Abstract
An efficient method for the preparation of new ethyl 3-amino-4-arylfuran-2-carboxylates is described. The synthesis proceeds via the corresponding hydroxyacrylonitrile sodium salt and an intermediate malonate vinyl ether.The last step of ring closure afforded the ethyl 3-amino-4-arylfuran-2-carboxylates in 15% to 40% yields.
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