Economical Synthesis of α-Amino Acids from a Novel Family of Easily Available Schiff Bases of Glycine Esters and 2-Hydroxybenzophenone
Yuri Belokon
1
,
Zalina Gugkaeva
1
,
Vladimir A Larionov
1, 2
,
Margarita Moskalenko
1
,
Victor Khrustalev
2
,
Yulia Nelyubina
1
,
Alexander Peregudov
1
,
Alan Tsaloev
3
,
Victor Maleev
1
2
Department of Inorganic Chemistry, People’s Friendship University of Russia (RUDN University)
|
3
Chemical Diversity Research Institute
Publication type: Journal Article
Publication date: 2017-11-09
scimago Q2
wos Q2
SJR: 0.559
CiteScore: 4.6
Impact factor: 2.3
ISSN: 00397881, 1437210X
Catalysis
Organic Chemistry
Abstract
We report a novel, efficient, and easily prepared substrate/precursor family of Schiff bases of various glycine esters with 2-hydroxybenzophenone, and their use for the synthesis of amino acids in quantitative yields. The Michael addition of the substrates to methyl acrylate gave two different types of product (cyclic or chain), depending on the nature of the base. Also, we demonstrated that one of the new substrates could be involved in an asymmetric version of the alkylation reaction (70% ee).
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15
Total citations:
15
Citations from 2024:
1
(6%)
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MLA
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GOST
Copy
Belokon Y. et al. Economical Synthesis of α-Amino Acids from a Novel Family of Easily Available Schiff Bases of Glycine Esters and 2-Hydroxybenzophenone // Synthesis. 2017. Vol. 50. No. 03. pp. 607-616.
GOST all authors (up to 50)
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Belokon Y., Gugkaeva Z., Larionov V. A., Moskalenko M., Khrustalev V., Nelyubina Y., Peregudov A., Tsaloev A., Maleev V. Economical Synthesis of α-Amino Acids from a Novel Family of Easily Available Schiff Bases of Glycine Esters and 2-Hydroxybenzophenone // Synthesis. 2017. Vol. 50. No. 03. pp. 607-616.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1055/s-0036-1590945
UR - http://www.thieme-connect.de/DOI/DOI?10.1055/s-0036-1590945
TI - Economical Synthesis of α-Amino Acids from a Novel Family of Easily Available Schiff Bases of Glycine Esters and 2-Hydroxybenzophenone
T2 - Synthesis
AU - Belokon, Yuri
AU - Gugkaeva, Zalina
AU - Larionov, Vladimir A
AU - Moskalenko, Margarita
AU - Khrustalev, Victor
AU - Nelyubina, Yulia
AU - Peregudov, Alexander
AU - Tsaloev, Alan
AU - Maleev, Victor
PY - 2017
DA - 2017/11/09
PB - Georg Thieme Verlag KG
SP - 607-616
IS - 03
VL - 50
SN - 0039-7881
SN - 1437-210X
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2017_Belokon,
author = {Yuri Belokon and Zalina Gugkaeva and Vladimir A Larionov and Margarita Moskalenko and Victor Khrustalev and Yulia Nelyubina and Alexander Peregudov and Alan Tsaloev and Victor Maleev},
title = {Economical Synthesis of α-Amino Acids from a Novel Family of Easily Available Schiff Bases of Glycine Esters and 2-Hydroxybenzophenone},
journal = {Synthesis},
year = {2017},
volume = {50},
publisher = {Georg Thieme Verlag KG},
month = {nov},
url = {http://www.thieme-connect.de/DOI/DOI?10.1055/s-0036-1590945},
number = {03},
pages = {607--616},
doi = {10.1055/s-0036-1590945}
}
Cite this
MLA
Copy
Belokon, Yuri, et al. “Economical Synthesis of α-Amino Acids from a Novel Family of Easily Available Schiff Bases of Glycine Esters and 2-Hydroxybenzophenone.” Synthesis, vol. 50, no. 03, Nov. 2017, pp. 607-616. http://www.thieme-connect.de/DOI/DOI?10.1055/s-0036-1590945.
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