Synthesis, volume 2005, issue 11, pages 1859-1875
Novel Approach to Isoindolo[2,1-a]quinolines: Synthesis of 1- and 3-Halo-Substituted 11-Oxo-5,6,6a,11-tetrahydroisoindolo[2,1-a]quinoline-10-carboxylic Acids
Publication type: Journal Article
Publication date: 2005-07-05
Journal:
Synthesis
scimago Q2
wos Q2
SJR: 0.582
CiteScore: 4.5
Impact factor: 2.2
ISSN: 00397881, 1437210X
Catalysis
Organic Chemistry
Abstract
A series of 1- and 3-halo-substituted isoindolo[2,1-a]quinolines were obtained by means of electrophilic cyclization of methallyl- and allyl-substituted isoindolo-7-carboxylic acids. The influence of halogen atoms on the stereochemistry of the formation of key intermediates, 3a,6-epoxyisoindoles, was studied.
Found
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