The Complex Nature of the Mechanism of Toxicity of Antibiotic Dithiacyclohexadiene Polyines (Thiarubrines) from the Asteraceae
Тип публикации: Journal Article
Дата публикации: 1989-02-01
SCImago Q2
WOS Q2
БС1
SJR: 0.456
CiteScore: 4.7
Impact factor: 2.1
ISSN: 00320943, 14390221
PubMed ID:
2717687
Organic Chemistry
Drug Discovery
Pharmacology
Pharmaceutical Science
Molecular Medicine
Complementary and alternative medicine
Analytical Chemistry
Краткое описание
Thiarubrine A, a dithiacyclohexadiene polyine from the roots of Chaenactis douglasii, and a related dithiacyclohexadiene from Rudbeckia hirta exhibit strong light-independent antibacterial and antifungal activity. This activity is enhanced by exposure to visible light. Visible light also converts the compounds to the corresponding thiophenes. These are antibiotic only when irradiated with UV-A. Dithiacyclohexadienes are the first polyines to exhibit such complex mechanisms of toxicity towards microorganisms.
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ГОСТ
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Constabel C., Towers G. The Complex Nature of the Mechanism of Toxicity of Antibiotic Dithiacyclohexadiene Polyines (Thiarubrines) from the Asteraceae // Planta Medica. 1989. Vol. 55. No. 01. pp. 35-37.
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Constabel C., Towers G. The Complex Nature of the Mechanism of Toxicity of Antibiotic Dithiacyclohexadiene Polyines (Thiarubrines) from the Asteraceae // Planta Medica. 1989. Vol. 55. No. 01. pp. 35-37.
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RIS
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TY - JOUR
DO - 10.1055/s-2006-961771
UR - https://doi.org/10.1055/s-2006-961771
TI - The Complex Nature of the Mechanism of Toxicity of Antibiotic Dithiacyclohexadiene Polyines (Thiarubrines) from the Asteraceae
T2 - Planta Medica
AU - Constabel, C.Peter
AU - Towers, G
PY - 1989
DA - 1989/02/01
PB - Georg Thieme Verlag KG
SP - 35-37
IS - 01
VL - 55
PMID - 2717687
SN - 0032-0943
SN - 1439-0221
ER -
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BibTex (до 50 авторов)
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@article{1989_Constabel,
author = {C.Peter Constabel and G Towers},
title = {The Complex Nature of the Mechanism of Toxicity of Antibiotic Dithiacyclohexadiene Polyines (Thiarubrines) from the Asteraceae},
journal = {Planta Medica},
year = {1989},
volume = {55},
publisher = {Georg Thieme Verlag KG},
month = {feb},
url = {https://doi.org/10.1055/s-2006-961771},
number = {01},
pages = {35--37},
doi = {10.1055/s-2006-961771}
}
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MLA
Скопировать
Constabel, C.Peter, and G Towers. “The Complex Nature of the Mechanism of Toxicity of Antibiotic Dithiacyclohexadiene Polyines (Thiarubrines) from the Asteraceae.” Planta Medica, vol. 55, no. 01, Feb. 1989, pp. 35-37. https://doi.org/10.1055/s-2006-961771.
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