Fischer reaction in the synthesis of indole derivatives of fusidic acid benzyl ester

Publication type: Proceedings Article
Publication date: 2022-02-04
AIP Publishing
SJR: 0.153
CiteScore: 0.5
Impact factor: —
ISSN: 0094243X, 15517616
Abstract
The Fischer reaction was used to synthesize 11-oxo-indole- and 11-oxo-Cl-indole derivatives of fusidic acid benzyl ester which are promising antimicrobial agents. It was found that the reaction of 3,11-diketo-benzylfusidate with phenylhydrazines proceeds chemoselectively and provides 2,3-fused indoles, whilst the 11-keto function does not undergo the cyclization.
Found 

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Salimova E. V., Tretyakova E., Parfenova L. V. Fischer reaction in the synthesis of indole derivatives of fusidic acid benzyl ester // AIP Conference Proceedings. 2022. Vol. 2390.
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Salimova E. V., Tretyakova E., Parfenova L. V. Fischer reaction in the synthesis of indole derivatives of fusidic acid benzyl ester // AIP Conference Proceedings. 2022. Vol. 2390.
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TY - CPAPER
DO - 10.1063/5.0069131
UR - https://doi.org/10.1063/5.0069131
TI - Fischer reaction in the synthesis of indole derivatives of fusidic acid benzyl ester
T2 - AIP Conference Proceedings
AU - Salimova, Elena V
AU - Tretyakova, Elena
AU - Parfenova, Lyudmila V.
PY - 2022
DA - 2022/02/04
PB - AIP Publishing
VL - 2390
SN - 0094-243X
SN - 1551-7616
ER -
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@inproceedings{2022_Salimova,
author = {Elena V Salimova and Elena Tretyakova and Lyudmila V. Parfenova},
title = {Fischer reaction in the synthesis of indole derivatives of fusidic acid benzyl ester},
year = {2022},
volume = {2390},
month = {feb},
publisher = {AIP Publishing}
}