Diastereoselective synthesis of novel 20-hydroxyecdysone dioxolane derivatives

R. G. Savchenko
, 
V. N. Odinokov
, 
L V Parfenova
Publication type: Proceedings Article
Publication date: 2022-02-04
AIP Publishing
SJR: 0.153
CiteScore: 0.5
Impact factor: —
ISSN: 0094243X, 15517616
Abstract
New dioxolane derivatives of ecdysteroids were synthesized by the acid-catalyzed reaction of 20-hydroxyecdysone with CHO(CH2)8CO2Me and o-FC6H5CHO. It was found that the reaction proceeds stereoselectively and provides 2,3-and 20,22-cyclic diacetals with R-configuration of novel stereogenic centers. The identification of the structure of the synthesized compounds was carried out by the means of 1D and 2D NMR spectroscopy, as well as MALDI TOF/TOF spectrometry.
Found 

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
0
Share
Cite this
GOST |
Cite this
GOST Copy
Savchenko R. G., Odinokov V. N., Parfenova L. V. Diastereoselective synthesis of novel 20-hydroxyecdysone dioxolane derivatives // AIP Conference Proceedings. 2022. Vol. 2390.
GOST all authors (up to 50) Copy
Savchenko R. G., Odinokov V. N., Parfenova L. V. Diastereoselective synthesis of novel 20-hydroxyecdysone dioxolane derivatives // AIP Conference Proceedings. 2022. Vol. 2390.
RIS |
Cite this
RIS Copy
TY - CPAPER
DO - 10.1063/5.0069194
UR - https://doi.org/10.1063/5.0069194
TI - Diastereoselective synthesis of novel 20-hydroxyecdysone dioxolane derivatives
T2 - AIP Conference Proceedings
AU - Savchenko, R. G.
AU - Odinokov, V. N.
AU - Parfenova, L V
PY - 2022
DA - 2022/02/04
PB - AIP Publishing
VL - 2390
SN - 0094-243X
SN - 1551-7616
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@inproceedings{2022_Savchenko,
author = {R. G. Savchenko and V. N. Odinokov and L V Parfenova},
title = {Diastereoselective synthesis of novel 20-hydroxyecdysone dioxolane derivatives},
year = {2022},
volume = {2390},
month = {feb},
publisher = {AIP Publishing}
}