Organofluorine chemistry: promising growth areas and challenges
Currently, the chemistry of organofluorine compounds is a leading and rapidly developing area of organic chemistry. Fluorine present in a molecule largely determines its specific chemical and biological properties. This thematic issue covers the trends of organofluorine chemistry that have been actively developed in Russia the last 15 – 20 years. The review describes nucleophilic substitution and heterocyclization reactions involving fluorinated arenes and quinones and skeletal cationoid rearrangements in the polyfluoroarene series. The transformations involving CF3-substituted carbocations and radical cations are considered. Heterocyclization and oxidative addition reactions of trifluoroacetamide derivatives and transformations of the organic moiety in polyfluorinated organoboranes and borates with retention of the carbon – boron bond are discussed. Particular attention is devoted to catalytic olefination using freons as an efficient synthetic route to fluorinated compounds. The application of unsymmetrical fluorine-containing N-heterocyclic carbene ligands as catalysts for olefin metathesis is demonstrated. A variety of classes of organofluorine compounds are considered, in particular, polyfluorinated arenes and 1,2-diaminobenzenes, 1-halo-2-trifluoroacetylacetylenes, α-fluoronitro compounds, fluorinated heterocycles, 2-hydrazinylidene-1,3-dicarbonyl derivatives, imines and silanes. The potential practical applications of organofluorine compounds in fundamental organic chemistry, materials science and biomedicine are outlined.
The bibliography includes 1019 references.
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Citations by journals
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Russian Chemical Bulletin
19 publications, 14.18%
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Journal of Fluorine Chemistry
15 publications, 11.19%
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Mendeleev Communications
12 publications, 8.96%
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Molecules
11 publications, 8.21%
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European Journal of Organic Chemistry
10 publications, 7.46%
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Russian Journal of Organic Chemistry
9 publications, 6.72%
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Russian Chemical Reviews
9 publications, 6.72%
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Journal of Organic Chemistry
4 publications, 2.99%
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Russian Journal of General Chemistry
4 publications, 2.99%
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Organic and Biomolecular Chemistry
3 publications, 2.24%
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Beilstein Journal of Organic Chemistry
3 publications, 2.24%
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Advances in Heterocyclic Chemistry
2 publications, 1.49%
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Journal of Chemical & Engineering Data
2 publications, 1.49%
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Chemistry of Heterocyclic Compounds
2 publications, 1.49%
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Journal of Organometallic Chemistry
2 publications, 1.49%
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2 publications, 1.49%
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1 publication, 0.75%
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Crystals
1 publication, 0.75%
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1 publication, 0.75%
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Nature Communications
1 publication, 0.75%
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Chemical Papers
1 publication, 0.75%
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SN Applied Sciences
1 publication, 0.75%
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Medicine in Drug Discovery
1 publication, 0.75%
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Bioorganic and Medicinal Chemistry Letters
1 publication, 0.75%
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Helvetica Chimica Acta
1 publication, 0.75%
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ChemPhysChem
1 publication, 0.75%
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Asian Journal of Organic Chemistry
1 publication, 0.75%
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Magnetic Resonance in Chemistry
1 publication, 0.75%
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Journal of Chemical Theory and Computation
1 publication, 0.75%
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Citations by publishers
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Elsevier
35 publications, 26.12%
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Springer Nature
25 publications, 18.66%
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Wiley
18 publications, 13.43%
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Pleiades Publishing
15 publications, 11.19%
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Multidisciplinary Digital Publishing Institute (MDPI)
14 publications, 10.45%
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Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
9 publications, 6.72%
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American Chemical Society (ACS)
8 publications, 5.97%
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Royal Society of Chemistry (RSC)
5 publications, 3.73%
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Beilstein-Institut
3 publications, 2.24%
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Walter de Gruyter
1 publication, 0.75%
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Thieme
1 publication, 0.75%
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