Russian Chemical Reviews, volume 88, issue 1, pages 59-98
NMR screening and studies of target - Ligand interactions
Publication type: Journal Article
Publication date: 2019-01-01
Journal:
Russian Chemical Reviews
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 7.7
ISSN: 0036021X, 14684837
DOI:
10.1070/RCR4836
General Chemistry
Abstract
Nuclear magnetic resonance (NMR) spectroscopy is one of the leading biophysical methods used in the search for and design of physiologically active compounds considered as potential drugs. The review concerns modern NMR techniques used to study the binding of low-molecular-mass compounds to biomacromolecular targets. The most promising methods of NMR screening and strategies for rational lead design are discussed. They were used to design drugs that have been approved for the use in medical practice or are in the final stages of clinical trials. Examples are given of the application of the fragment-based drug design and NMR screening techniques to the design of novel drugs.
The bibliography includes 252 references.
Citations by journals
|
1
2
3
|
|
|
Russian Chemical Reviews
|
Russian Chemical Reviews
3 publications, 42.86%
|
|
FEBS Journal
|
FEBS Journal
1 publication, 14.29%
|
|
Molecular Biology
|
Molecular Biology
1 publication, 14.29%
|
|
Frontiers in Molecular Biosciences
|
Frontiers in Molecular Biosciences
1 publication, 14.29%
|
|
Mendeleev Communications
|
Mendeleev Communications
1 publication, 14.29%
|
|
1
2
3
|
Citations by publishers
|
1
2
3
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
3 publications, 42.86%
|
|
Wiley
|
Wiley
1 publication, 14.29%
|
|
Pleiades Publishing
|
Pleiades Publishing
1 publication, 14.29%
|
|
Frontiers Media S.A.
|
Frontiers Media S.A.
1 publication, 14.29%
|
|
Elsevier
|
Elsevier
1 publication, 14.29%
|
|
1
2
3
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2020,2021,2022],"ids":[0,0,0],"codes":[0,0,0],"imageUrls":["","",""],"datasets":[{"label":"Citations number","data":[3,2,2],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6"],"percentage":["42.86","28.57","28.57"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Russian Chemical Reviews","FEBS Journal","Molecular Biology","Frontiers in Molecular Biosciences","Mendeleev Communications"],"ids":[23802,9481,1134,3133,5294],"codes":[0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/9Mus3KG1Tkd7Bwaurt8H3RwWh0CxRlGoO6ng9UK1_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp"],"datasets":[{"label":"","data":[3,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[42.86,14.29,14.29,14.29,14.29],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii","Wiley","Pleiades Publishing","Frontiers Media S.A.","Elsevier"],"ids":[9422,11,101,208,17],"codes":[0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/9Mus3KG1Tkd7Bwaurt8H3RwWh0CxRlGoO6ng9UK1_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp"],"datasets":[{"label":"","data":[3,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[42.86,14.29,14.29,14.29,14.29],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Polshakov V. I., Batuev E. A., Mantsyzov A. B. NMR screening and studies of target - Ligand interactions // Russian Chemical Reviews. 2019. Vol. 88. No. 1. pp. 59-98.
GOST all authors (up to 50)
Copy
Polshakov V. I., Batuev E. A., Mantsyzov A. B. NMR screening and studies of target - Ligand interactions // Russian Chemical Reviews. 2019. Vol. 88. No. 1. pp. 59-98.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1070/RCR4836
UR - https://doi.org/10.1070%2FRCR4836
TI - NMR screening and studies of target - Ligand interactions
T2 - Russian Chemical Reviews
AU - Polshakov, Vladimir I
AU - Batuev, Evgeniy A
AU - Mantsyzov, Alexey B.
PY - 2019
DA - 2019/01/01 00:00:00
PB - Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
SP - 59-98
IS - 1
VL - 88
SN - 0036-021X
SN - 1468-4837
ER -
Cite this
BibTex
Copy
@article{2019_Polshakov,
author = {Vladimir I Polshakov and Evgeniy A Batuev and Alexey B. Mantsyzov},
title = {NMR screening and studies of target - Ligand interactions},
journal = {Russian Chemical Reviews},
year = {2019},
volume = {88},
publisher = {Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii},
month = {jan},
url = {https://doi.org/10.1070%2FRCR4836},
number = {1},
pages = {59--98},
doi = {10.1070/RCR4836}
}
Cite this
MLA
Copy
Polshakov, Vladimir I., et al. “NMR screening and studies of target - Ligand interactions.” Russian Chemical Reviews, vol. 88, no. 1, Jan. 2019, pp. 59-98. https://doi.org/10.1070%2FRCR4836.
Profiles