Open Access
Recent advances in antifungal drug discovery based on polyene macrolide antibiotics
Тип публикации: Journal Article
Дата публикации: 2018-12-01
scimago Q1
wos Q1
white level БС1
SJR: 0.811
CiteScore: 12.9
Impact factor: 6
ISSN: 0036021X, 14684837
General Chemistry
Краткое описание
The review summarizes recent advances in the synthesis of new derivatives of polyene macrolide antibiotics by chemical modification and genetic engineering methods, results of structure – activity relationship studies and progress in the development of effective and safe drug formulations of this class of antibiotics. Attention is focused on structural changes of polyenes, resulting in a significant decrease in toxicity with retention or even enhancement of antifungal activity. Current concepts on the mechanisms of biological action of these antiobiotics in terms of their therapeutic activity and toxicity are considered.
The bibliography includes 77 references.
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Всего цитирований:
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(11.54%)
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ГОСТ |
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BibTex |
MLA
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ГОСТ
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Omelchuk O. A. et al. Recent advances in antifungal drug discovery based on polyene macrolide antibiotics // Russian Chemical Reviews. 2018. Vol. 87. No. 12. pp. 1206-1225.
ГОСТ со всеми авторами (до 50)
Скопировать
Omelchuk O. A., Tevyashova A., Shchekotikhin A. E. Recent advances in antifungal drug discovery based on polyene macrolide antibiotics // Russian Chemical Reviews. 2018. Vol. 87. No. 12. pp. 1206-1225.
Цитировать
RIS
Скопировать
TY - JOUR
DO - 10.1070/rcr4841
UR - https://doi.org/10.1070/rcr4841
TI - Recent advances in antifungal drug discovery based on polyene macrolide antibiotics
T2 - Russian Chemical Reviews
AU - Omelchuk, Olga A
AU - Tevyashova, Anna
AU - Shchekotikhin, Andrei E
PY - 2018
DA - 2018/12/01
PB - Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
SP - 1206-1225
IS - 12
VL - 87
SN - 0036-021X
SN - 1468-4837
ER -
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BibTex (до 50 авторов)
Скопировать
@article{2018_Omelchuk,
author = {Olga A Omelchuk and Anna Tevyashova and Andrei E Shchekotikhin},
title = {Recent advances in antifungal drug discovery based on polyene macrolide antibiotics},
journal = {Russian Chemical Reviews},
year = {2018},
volume = {87},
publisher = {Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii},
month = {dec},
url = {https://doi.org/10.1070/rcr4841},
number = {12},
pages = {1206--1225},
doi = {10.1070/rcr4841}
}
Цитировать
MLA
Скопировать
Omelchuk, Olga A., et al. “Recent advances in antifungal drug discovery based on polyene macrolide antibiotics.” Russian Chemical Reviews, vol. 87, no. 12, Dec. 2018, pp. 1206-1225. https://doi.org/10.1070/rcr4841.
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