Open Access
Open access
volume 90 issue 12 pages 1566-1623

Coordination compounds of biogenic metals as cytotoxic agents in cancer therapy

Publication typeJournal Article
Publication date2021-12-01
scimago Q1
wos Q1
SJR0.811
CiteScore12.9
Impact factor6.0
ISSN0036021X, 14684837
General Chemistry
Abstract

The review summarizes the data on the structures and methods for the synthesis of compounds with anticancer activity based on biogenic metals, which can replace platinum drugs prevailing in cytotoxic therapy. The main focus is given to the comparison of the mechanisms of the cytotoxic action of these complexes, their efficacy and prospects of their use in clinical practice. This is the first systematic review of cytotoxic zinc, iron, cobalt and copper compounds. The structure – activity relationships and the mechanisms of antitumour action are formulated for each type of metal complexes.

The bibliography includes 181 references.

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GOST |
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GOST Copy
Guk D. A., Krasnovskaya O. O., Beloglazkina E. K. Coordination compounds of biogenic metals as cytotoxic agents in cancer therapy // Russian Chemical Reviews. 2021. Vol. 90. No. 12. pp. 1566-1623.
GOST all authors (up to 50) Copy
Guk D. A., Krasnovskaya O. O., Beloglazkina E. K. Coordination compounds of biogenic metals as cytotoxic agents in cancer therapy // Russian Chemical Reviews. 2021. Vol. 90. No. 12. pp. 1566-1623.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1070/RCR5016
UR - https://iopscience.iop.org/article/10.1070/RCR5016
TI - Coordination compounds of biogenic metals as cytotoxic agents in cancer therapy
T2 - Russian Chemical Reviews
AU - Guk, Dmitry A.
AU - Krasnovskaya, Olga O.
AU - Beloglazkina, Elena K.
PY - 2021
DA - 2021/12/01
PB - Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
SP - 1566-1623
IS - 12
VL - 90
SN - 0036-021X
SN - 1468-4837
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2021_Guk,
author = {Dmitry A. Guk and Olga O. Krasnovskaya and Elena K. Beloglazkina},
title = {Coordination compounds of biogenic metals as cytotoxic agents in cancer therapy},
journal = {Russian Chemical Reviews},
year = {2021},
volume = {90},
publisher = {Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii},
month = {dec},
url = {https://iopscience.iop.org/article/10.1070/RCR5016},
number = {12},
pages = {1566--1623},
doi = {10.1070/RCR5016}
}
MLA
Cite this
MLA Copy
Guk, Dmitry A., et al. “Coordination compounds of biogenic metals as cytotoxic agents in cancer therapy.” Russian Chemical Reviews, vol. 90, no. 12, Dec. 2021, pp. 1566-1623. https://iopscience.iop.org/article/10.1070/RCR5016.