Open Access
,
volume 114
,
issue 16
Delivering strong 1 H nuclear hyperpolarization levels and long magnetic lifetimes through signal amplification by reversible exchange
Publication type: Journal Article
Publication date: 2017-04-04
scimago Q1
wos Q1
SJR: 3.414
CiteScore: 16.5
Impact factor: 9.1
ISSN: 00278424, 10916490
PubMed ID:
28377523
Multidisciplinary
Abstract
Significance
The study of molecules and materials is of great significance to both science and human welfare. The noninvasive techniques of NMR and MRI reflect two of the most important methods to study them. However, both of these approaches are insensitive, and hyperpolarization methods to improve sensitivity are needed to access new applications. The hyperpolarization approach signal amplification by reversible exchange is used to produce a signal that is 100,000 times larger than that which would be seen on a routine clinical MRI scanner under Boltzmann equilibrium conditions. By revealing the broad scope of this approach we demonstrate its potential for the future diagnostic detection of metabolites, drugs, and many other small molecules.
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Metrics
133
Total citations:
133
Citations from 2025:
7
(5.26%)
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GOST
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Rayner P. J. et al. Delivering strong 1 H nuclear hyperpolarization levels and long magnetic lifetimes through signal amplification by reversible exchange // Proceedings of the National Academy of Sciences of the United States of America. 2017. Vol. 114. No. 16.
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Rayner P. J., Burns M. J., Olaru A. M., Norcott P., Fekete M., Green G. G. R., Highton L. A. R., Mewis R. E., Duckett S. G. Delivering strong 1 H nuclear hyperpolarization levels and long magnetic lifetimes through signal amplification by reversible exchange // Proceedings of the National Academy of Sciences of the United States of America. 2017. Vol. 114. No. 16.
Cite this
RIS
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TY - JOUR
DO - 10.1073/pnas.1620457114
UR - https://doi.org/10.1073/pnas.1620457114
TI - Delivering strong 1 H nuclear hyperpolarization levels and long magnetic lifetimes through signal amplification by reversible exchange
T2 - Proceedings of the National Academy of Sciences of the United States of America
AU - Rayner, Peter J.
AU - Burns, Michael J.
AU - Olaru, Alexandra M
AU - Norcott, Philip
AU - Fekete, Marianna
AU - Green, Gary G R
AU - Highton, Louise A R
AU - Mewis, Ryan E
AU - Duckett, Simon G.
PY - 2017
DA - 2017/04/04
PB - Proceedings of the National Academy of Sciences (PNAS)
IS - 16
VL - 114
PMID - 28377523
SN - 0027-8424
SN - 1091-6490
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2017_Rayner,
author = {Peter J. Rayner and Michael J. Burns and Alexandra M Olaru and Philip Norcott and Marianna Fekete and Gary G R Green and Louise A R Highton and Ryan E Mewis and Simon G. Duckett},
title = {Delivering strong 1 H nuclear hyperpolarization levels and long magnetic lifetimes through signal amplification by reversible exchange},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
year = {2017},
volume = {114},
publisher = {Proceedings of the National Academy of Sciences (PNAS)},
month = {apr},
url = {https://doi.org/10.1073/pnas.1620457114},
number = {16},
doi = {10.1073/pnas.1620457114}
}